Antibiotics Flashcards
(5 cards)
1
Q
How do antibiotics work?
A
inhibiting prokaryotic protein synthesis by directly binding rRNA molecule pockets.
2
Q
Hygromycin B
A
erros in translation
3
Q
Spectinomycin
A
blocks tRNA translocation so elongation cannot occur.
4
Q
Streptogramin B
A
prevent elongation of nascent pps
5
Q
Puromycin
A
disrupts peptide bond formation by resembling the aminoacyl end of charged tRNA, binding the A site and participating in the peptide bind formation. It gets incorporated, translocation cannot our and the chain is terminated prematurely.
