Initiation - Eukaryotic

Question 1

Step 1

Answer 1

Ribosome is prepped with eIFs.

Question 2

Step 2

Answer 2

tRNA is aminoacylated with Met and binds ribosome

Question 3

Step 3

Answer 3

More eIFs bind small subunit to form the final preinitiation complex

Question 4

Step 4

Answer 4

mRNA with cap binding complex binds pre initiation complex to form the initiation complex.

Question 5

Step 5

Answer 5

Met-tRNA in small subunit binds to mRNA and recognises start codon and eIFs dissociate.

Question 6

Step 6

Answer 6

Large subunit binds small subunit with Met-tRNA at P site. Only the p site can recognize Met-tRNA