Antibiotics Flashcards
(38 cards)
Gram - stains what color?
Pink/red
Gram + stains what color?
Blue/purple
-cidal =
Bacterial killing
-static =
Inhibits bacteria growth
Broad spectrum =
Kills both gram + and -
Narrow spectrum =
Only gram + or only gram -
MIC stands for what?
Minimum inhibitory concentration
What does MIC mean?
The smallest concentration effective against microbes
Kirby-bauer test
Uses abx discs in an incubated plate of bacteria to test what abx affects bacteria
Beta lactamase
Enzyme created by bacteria to break down beta lactam ring
Potentiated drug
Combo of drugs that enhances effects of both drugs
Cell wall agent abx
Penicillins, cephalosporins, polypeptides, glycopeptides, carbapenems, monobactams
Two narrow spectrum, naturally occurring penicillins
Pen G and V
Or penicillin that doesn’t require being given on an empty stomach
Amoxicillin
Broad spectrum penicillins
ampicillin amoxicillin piperacillin carbenicillin ticarcillin
Penicillins are more effective against gram + or gram - bacteria?
Gram +
Example of potentiated penicillin
Clavamox
How are cephalosporins classified
4 Generations
How do the 4 cephalosporin generations work?
The greater the generation, the more broad spectrum and more se
Beta lactimase resistant penicillins
oxacillin
dicloxacillin
cloxacillin
nafcillin
Generic examples of cephalosporins
cefazolin
cephalexin
cefpime
In companion animal medicine, bacitracin is used by what route of admin?
Topical
What antibiotic is rarely used in nonhuman species so that we don’t help build resistance
Vancomycin
What are the first generation cephalosporins
cefadroxil
cefazolin
cephalexin