antibiotics Flashcards

(41 cards)

1
Q

-cillins

A

CWS inhibiters, great on gram +, work on some gram -, longer names are stronger

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2
Q

carbepenen

A

CWS inhibiter, good beta lactam for gram -

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3
Q

imipenen

A

CWS inhibiter, beta lactam resistent to beta lactamase

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4
Q

ampicillin and amoxicillin

A

CWS inhibiter, have an extended spectra, used in many infections

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5
Q

single syllable -cillins

A

CWS, used against staph

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6
Q

vancomycin

A

CWS, works on almost all G+, but no G-, super powerful, do other stuff before this one

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7
Q

isoniazid and ethambutol

A

CWS, disrupts the “PPG” of the gram (na)

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8
Q

Pretomanid

A

CWS, used on tuberculosis only

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9
Q

bacitracin and polymyxin B

A

CWS, pore formers, work on simple gram + and -, neomycin can be added, only topical

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10
Q

daptomycin

A

CWS, gram +, works well on staphs

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11
Q

Chloramphenicol

A

PSI, 50s, kills everything including red blood cells, only in SEVERE cases

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12
Q

Lincomycin and Clindamycin

A

PSI, 50s, used for shock, can cause c. diff

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13
Q

Erythromycin and Azithromycin

A

PSI, 50s, macrolide family, works well on gram + and NA

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14
Q

Tetracycline, doxycycline, minocycline

A

PSI, 30s, from aureomycin, very broad spectrum but very high toxicity, not for kids, teratogenic

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15
Q

aminoglycosides

A

PSI, 30s, serious gram -, teratogenic, cannot be taken orally

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16
Q

synercid

A

PSI, 50s, synthetic, good for staphs, enterococcus, and strep

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17
Q

oxazalidones

A

PSI, 50s, Zyvox, last line of gram +

18
Q

sulfonamides

A

AM, mimics PBA so no folate, competitive inhibition, often used in conjugation with trimethoprim, not for pregnant women

19
Q

trimethoprim

A

AM, non-competitive, used in conjugation with sulfonamides, not for pregnant women

20
Q

Bactrim

A

AM, sulfa and trimethoprim, used for UTIs

21
Q

ciprofloxacin

A

RI, prophylaxis, very broad spectrum, before surgery

22
Q

norfloxacin

A

RI, gram + and -, UTIs

23
Q

levofloxacin

A

RI, STDs, skin infections, systemic infections

24
Q

rifampin

A

RI, gram + and -, tuberculosis, pneumonias, UTIs, gastroenteritis

25
Acyclovir and valacyclovir
DNA viral inhibitor
26
foscarnet
DNA viral inhibitor
27
ribavirin
RNA viral inhibitor
28
NRTIs
competitive inhibition, -vudine and -avir
29
NNRTIs
non-competitive inhibition
30
NtARTIs
-fovir
31
zanamivir
AV, competitive inhibitor for influenza
32
Interferons
AV, non-competitive for hepatitis
33
clostrimazole and miconazole
AF, topical ointments, lowest grade
34
ketoconazole
AF, topical and oral, middle grade
35
fluconazole
AF, only for AIDs, gets to the CSF
36
amphotericin B
AF, high toxicity, only if systemic
37
quinine and artemisinin
AP, anti-malarial, plant based, replaces by two others with quin in the name
38
metronidazole
AP, flagyl
39
pyrantel pamoate
AH, pinworms, low power
40
mebendazole and thiabendazole
AH, good on hookworm and other worms
41
ivermectin
AH, good on worms as well as live, scabies, and rosacea