Antibiotics Guidance

Question 1

Pneumonia ABX of choice

Answer 1

Amoxicillin
or
Doxycycline
Moderate- amoxicillin + clarithromycin

Question 2

COPD exacerbation abx of choice

Answer 2

Mild- amoxicillin
Doxycycline
Severe- co-trimoxazole

Question 3

Cdiff antibiotic

Answer 3

Oral Metronidazole 400mg 8 hourly

severe or no improvement- oral vancomycin

Question 4

Intraabdominal sepsis abx?

Answer 4

Gentamicin IV + metronidazole IV + Amoxicillin IV

Question 5

Cellulitis abx?

Answer 5

Limited soft tissue infection- Oral flucloxacillin (or clarithromycin)

Moderate to severe cellulitits- flucloxacillin IV (allergy- vancomycin)

Question 6

Sepsis of unknown source

Answer 6

Amoxicillin IV + Gentamicin IV ± metronidazole (penicillin allergy- gentamicin + vancomycin ± metronidazole

Question 7

Neutropenic sepsis abx?

Answer 7

Piperacillin/ Tazobactam 4.5g 6hourly IV

allergy ceftrazidime IV

Question 8

Meningitis abx?

Answer 8

Ceftriaxone 2g 12hourly IV
(allergy- chloramphenicol)
If >55 cover listeria + amoxicillin

+ dexamethasone IV for 4 days

Question 9

Endocarditis abx?

Answer 9

Amoxicillin 2g IV 4 hourly (allergy- vancomycin)

± gentamicin IV

Question 10

Drugs that can cause C-diff

Answer 10

Cephalosporins
Co-amoiclav
Ciprofloxacin
Clindamycin