Cardiac Drugs

Question 1

ACEi

Monitoring, Interactions, side-effects

Answer 1

M- U&Es prior and 1-2 weeks after
I-nephrotoxic, NSAIDS
SE- cough, hypotensions, hyperkalamia, angioedema

Question 2

ARBs

Monitoring, Interactions, side-effects

Answer 2

M- U&Es before and after
I-NSAIDs, nephrotoxics
SE- hypotension, hyperkalaemia, renal impairment, angioedema

Question 3

Beta blockers

Cautions, Interactions, side-effects

Answer 3

C-Asthma, COPD, 2nd or 3rd degree heart block, sick sinus ysndrome, uncontrolled HF, bradycardia, hypotension, metabolic acidosis, PAD
I-verapamil
SE-fatigue, headache, dizziness, erectile dysfunction, sleep disturbances and nightmares, cold peripheries

Question 4

CCB

Answer 4

I-digioxin, betablockers, theophylline, anti-epileptic drugs
SE-headache, flushing, abdo pian, hypotension, tachycardia, fatigue, peripheral oedema, cold peripheries, bradycardia, impotence (felodipine)
Counselling- dont eat grapefruit

Question 5

Digoxin

Answer 5

M- digoxin levels, U&Es, eGFR, HR

SE- GI disturbance, dizziness, n,v, blurred or yellow vision, rash

Question 6

Nitrates

Answer 6

CI- severe AS

SE- phypotension, tolerance, nausea, headahces

Question 7

Statins

Answer 7

Cautions- not in pregnancy, lower dose in renal and lover failire
Interactions- should be withheld when on clarithromycin
M- fasting lipids before, TFTs before statins, lipids 3 months after
SE- headahce, GI disturbamce, myalgia, LFTs rise, rhabdomyolysis