ANTIBIOTICS, INTRACANAL MEDICAMENTS

Question 1

selectively suppresses the growth of or kill other
microorganisms at very low concentrations

A. Antibiotics
B. Antimicrobial
Agents
C. Chemotherapy

Answer 1

A

Question 2

synthetic as well as naturally obtained drugs that
attenuate microorganisms

A. Antibiotics
B. Antimicrobial
Agents
C. Chemotherapy

Answer 2

B

Question 3

treatment of synthetic infections with specific drugs that selectively suppress the infecting microorganisms without significantly affecting the host

A. Antibiotics
B. Antimicrobial
Agents
C. Chemotherapy

Answer 3

C

Question 4

gave the idea that if certain dyes could selectively stain microbes, they could also be selectively toxic to these
organisms

A. Paul Ehrlich
B. Louis Pasteur
C. Gerhard Domagk
D. Alexander Flemming
E. Ernst Boris Chain and Howard Walter Florey
F. Waksman and Colleagues

Answer 4

A

Question 5

→ he tried methylene blue, trypan red, etc.

→he developed arsphenamine and neoarsphenamine in
1909 for syphilis

→he coined the term “chemotherapy”

A. Paul Ehrlich
B. Louis Pasteur
C. Gerhard Domagk
D. Alexander Flemming
E. Ernst Boris Chain and Howard Walter Florey
F. Waksman and Colleagues

Answer 5

A

Question 6

demonstrated the phenomenon of antibiosis (growth of anthrax
bacilli in urine was inhibited by
air-borne bacteria)

A. Paul Ehrlich
B. Louis Pasteur
C. Gerhard Domagk
D. Alexander Flemming
E. Ernst Boris Chain and Howard Walter Florey
F. Waksman and Colleagues

Answer 6

B

Question 7

the therapeutic effect of prontosil

A. Paul Ehrlich
B. Louis Pasteur
C. Gerhard Domagk
D. Alexander Flemming
E. Ernst Boris Chain and Howard Walter Florey
F. Waksman and Colleagues

Answer 7

C

Question 8

discovered penicillin

A. Paul Ehrlich
B. Louis Pasteur
C. Gerhard Domagk
D. Alexander Flemming
E. Ernst Boris Chain and Howard Walter Florey
F. Waksman and Colleagues

Answer 8

D

Question 9

clinical use of penicillin

A. Paul Ehrlich
B. Louis Pasteur
C. Gerhard Domagk
D. Alexander Flemming
E. Ernst Boris Chain and Howard Walter Florey
F. Waksman and Colleagues

Answer 9

E

Question 10

discovered streptomycin

A. Paul Ehrlich
B. Louis Pasteur
C. Gerhard Domagk
D. Alexander Flemming
E. Ernst Boris Chain and Howard Walter Florey
F. Waksman and Colleagues

Answer 10

F

Question 11

Drugs that Inhibits Cell Wall Synthesis

Answer 11

→
penicillin
→
cephalosporin
→
vancomycin
→
bacitracin

Question 12

Cause Leakage from Cell
Membrane

Answer 12

polypeptide

polyenes

Question 13

Inhibit Protein Synthesis

Answer 13

→
tetracycline
→
chloramphenicol
→
macrolides

Question 14

Mis-Reading of m-RNA

Answer 14

aminoglycosides

Question 15

Inhibit DNA Gyrase

Answer 15

fluoroquinolones

Question 16

Interfere with DNA Function

Answer 16

→
rifampicin
→
metronidazole

Question 17

Interfere with DNA Synthesis

Answer 17

→
acyclovir
→
zidovudine
→
idoxuridine

Question 18

Interfere with Intermediatory
Metabolism

Answer 18

→
sulfonamide
→
ethambutol

Question 19

Bacteriostatic drugs

Answer 19

→sulfonamides
→erythromycin
→tetracyclines
→ethambutol
→chloramphenicol
→clindamycin

(CHLO,CLIN,ETH,ERY,SUL,TE)

Question 20

Bactericidal drugs

Answer 20

→penicillin
→cephalosporin
→aminoglycosides
→vancomycin
→metronidazole
→cotrimoxazole

(Ami, co,ce,me,pe,van)

Question 21

Narrow-Spectrum drugs

Answer 21

→
penicillin-G
→
streptomycin
→
erythromycin

Question 22

Extended-Spectrum

Answer 22

→
ampicillin
→
amoxicillin

Question 23

Broad-Spectrum

Answer 23

→
tetracyclines
→
chloramphenicol

Question 24

T/f

bacterial invasion of dentinal tubules occurs more rapidly in
non-vital teeth than in vital ones

Answer 24

T

Question 25

WHEN DO YOU NEED DRUGS TO KILL THE BUGS?

Answer 25

→fever > 38 C or 100 F →malaise →lymphadenopathy →trismus →increased swelling →cellulitis →osteomyelitis →persistent infection

Question 26

T/f incision and drainage is indicated for any infection marked by cellulitis

Answer 26

T

Question 27

T/f for diseases with unknown microbial causes, empirical therapy may be used

Answer 27

T

Question 28

→systemic administration of antibiotics is generally recommended in order to prevent the harmful effects of bacterial contamination →antibiotics decrease the incidence of inflammatory root resorption but have a limited, or no effect on the pulp A. TOOTH AVULSION B. FLARE-UPS

Answer 28

A

Question 29

gram-negative obligate anaerobic rods o porphyromonas spp o prevotella spp A. TOOTH AVULSION B. FLARE-UPS

Answer 29

B

Question 30

major contributor to gingivalis A. prevotella spp B. porphyromonas spp

Answer 30

porphyromonas spp

Question 31

involves oral cavity, GUT, vagina microbiota–periodontitis) A. prevotella spp B. porphyromonas spp

Answer 31

prevotella spp

Question 32

a life-threatening disease with substantial morbidity and mortality which affects individuals with underlying structural cardiac defects who develop bacteremia

Answer 32

INFECTIVE ENDOCARDITIS

Question 33

most other congenital cardiac malformations not otherwise indicated A. HIGH-RISK CATEGORY B. MODERATE-RISK CATEGORY

Answer 33

B

Question 34

→. acquired valvular dysfunction →hypertrophic cardiomyopathy A. HIGH-RISK CATEGORY B. MODERATE-RISK CATEGORY

Answer 34

B

Question 35

mitral valve prolapse with regurgitation and/or thickened valve leaflets A. HIGH-RISK CATEGORY B. MODERATE-RISK CATEGORY

Answer 35

B

Question 36

→complex, cyanotic congenital heart disease A. HIGH-RISK CATEGORY B. MODERATE-RISK CATEGORY

Answer 36

A

Question 37

surgically constructed systemic pulmonary shunts A. HIGH-RISK CATEGORY B. MODERATE-RISK CATEGORY

Answer 37

A

Question 38

T/f DENTAL PROCEDURES CONSIDERED FOR ANTIBIOTIC PROPHYLAXIS IN SUSCEPTIBLE PATIENTS HIGH-RISK CATEGORY →subgingival placement of antibiotic fibers or strips →initial placement of orthodontic bands but not brackets

Answer 38

T

Question 39

T/f DENTAL PROCEDURES CONSIDERED FOR ANTIBIOTIC PROPHYLAXIS IN SUSCEPTIBLE PATIENTS HIGH-RISK CATEGORY →intraligamentary local anesthetic injections

Answer 39

T

Question 40

T/f PROCEDURES NOT RECOMMENDED FOR PROPHYLAXIS → placement of rubber dams →taking oral impressions →fluoride treatments →taking oral radiographs

Answer 40

T

Question 41

PARTIAL LIST OF DRUGS USUALLY COMPATIBLE WITH BOTH PREGNANCY AND BREAST-FEEDING →local anesthetics including: (3)

Answer 41

Lidocaine, Etidocaine and Prilocaine

Question 42

PBSC

Answer 42

Penicillin, Bacitracin, Streptomycin, and Caprylate Sodium

Question 43

all compounds were suspended in a silicone vehicle o Grossman Polyantibiotic Paste o Tetracycline o Ledermix o Septomixine Forte o MTAD o Tetraclean o Triple Antibiotic Paste o Clindamycin o Odontopaste

Answer 43

Grossman Polyantibiotic Paste

Question 44

gram (+) organisms A. Penicillin B. Bacitracin C. Streptomycin D. Caprylate Sodium

Answer 44

A

Question 45

penicillin-resistant strains A. Penicillin B. Bacitracin C. Streptomycin D. Caprylate Sodium

Answer 45

B

Question 46

gram (-) organisms A. Penicillin B. Bacitracin C. Streptomycin D. Caprylate Sodium

Answer 46

C

Question 47

yeasts A. Penicillin B. Bacitracin C. Streptomycin D. Caprylate Sodium

Answer 47

D

Question 48

the composition was ineffective against anaerobic species o Grossman Polyantibiotic Paste o Tetracycline o Ledermix o Septomixine Forte o MTAD o Tetraclean o Triple Antibiotic Paste o Clindamycin o Odontopaste

Answer 48

o Grossman Polyantibiotic Paste

Question 49

SEPTOMIXINE FORTE contains two antibiotics

Answer 49

neomycin and polymyxin B sulphate

Question 50

2 LEDERMIX PASTE

Answer 50

Triamcinolone Democlocycline

Question 51

anti-inflammatory action A. Triamcinolone B. Democlocycline

Answer 51

A

Question 52

inhibits clastic cells (osteoclasts, cementoclasts, and dentinoclasts) A. Triamcinolone B. Democlocycline

Answer 52

A

Question 53

concentration of 1.0% A. Triamcinolone B. Democlocycline

Answer 53

A

Question 54

antimicrobial action A. Triamcinolone B. Democlocycline

Answer 54

B

Question 55

concentration of 3.21% A. Triamcinolone B. Democlocycline

Answer 55

B

Question 56

→effective in preventing inflammatory resorption in avulsed teeth →pain management o Grossman Polyantibiotic Paste o Tetracycline o Ledermix o Septomixine Forte o MTAD o Tetraclean o Triple Antibiotic Paste o Clindamycin o Odontopaste

Answer 56

Ledermix

Question 57

used in the revitalization regeneration process o Grossman Polyantibiotic Paste o Tetracycline o Ledermix o Septomixine Forte o MTAD o Tetraclean o Triple Antibiotic Paste o Clindamycin o Odontopaste

Answer 57

o Triple Antibiotic Paste

Question 58

TRIPLE ANTIBIOTIC PASTE

Answer 58

Metronidazole + Ciprofloxacin + Minocycline

Question 59

an intracanal dressing

Answer 59

LEDERMIX PASTE + CALCIUM HYDROXIDE

Question 60

T/f TRIPLE ANTIBIOTIC PASTE DISADVANTAGES →it may cause bacterial resistance

Answer 60

T

Question 61

→to remove the smear layer from instrumented root canal walls →used as intracanal medicaments A. TETRACYCLINES B. MTAD C. TETRACLEAN

Answer 61

A

Question 62

capable of removing the smear layer and disinfection of the root canal system A. TETRACYCLINES B. MTAD C. TETRACLEAN

Answer 62

B

Question 63

T/f Odontopaste is most effectin enterococcus faecalis

Answer 63

T

Question 64

a temporary placement of medicaments with good biocompatibility into the root canals for the purpose of inhibiting of bacteria

Answer 64

INTRACANAL MEDICAMENTS

Question 65

PROPERTIES OF AN IDEAL INTRACANAL MEDICAMENT

Answer 65

(1) It should be an effective antimicrobial agent (2) It should be non-irritating to periradicular tissues (3) It should remain stable in solution (8) It should not stain tooth structure (4) It should have a prolonged antimicrobial effect (5) It should be active in the presence of blood, serum and protein derivatives of tissue (6) It should have a low surface tension (7) It should not interfere with the repair of periradicular tissue 9) It should not induce cell-mediated immune response

Question 66

oldest microbial agent

Answer 66

PHENOLS

Question 67

highly toxic, mutagenic and cariogenic

Answer 67

FORMALDEHYDE

Question 68

T/f formaldehyde is volatile and releases antimicrobial vapor when placed on cotton pellet for pulp chamber disinfection

Answer 68

T

Question 69

used as irrigant and intracanal dressing in the form of Chlorine and Iodine

Answer 69

HALOGEN

Question 70

also used as disinfectant for immature teeth with apical periodontitis

Answer 70

TRIPLE ANTIBIOTIC PASTE

Question 71

T/f the main characteristic of CaOH is it contains high pH, broad spectrum antimicrobial agent and antimicrobial action

Answer 71

T

Question 72

promote tissue healing, it is biocompatible and has antimicrobial properties and chemical composition closely resembles the mineral of human bone and dentin A. Bioactive Glass B. Ozonised Oil C. Octenidine Dihydrochloride

Answer 72

A

Question 73

may be used as antimicrobial but less effective than NaOCL A. Bioactive Glass B. Ozonised Oil C. Octenidine Dihydrochloride

Answer 73

B

Question 74

effective with eradication of S. Epidermidis A. Bioactive Glass B. Ozonised Oil C. Octenidine Dihydrochloride

Answer 74

C