Flashcards in Antibotics Exam 3 Deck (14)
Minimal Inhibitory Concentration (MIC)
The minimum drug conc. at which the bacterial population is inhibited to prevent visual growth.
Minimal Bactericidal Concentration (MBC)
The minimum drug conc. at which the bacterial population is killed.
What antimicrobial is the most toxic to humans?
Natural antibiotics are more toxic and less effective. Synthetic are loss toxic and more effective.
True or False? All antibiotics are antimicrobials, but not all antimicrobials are antibiotics.
Broad spectrum antibacterials are effective against...
List the examples.
Gram pos and Gram neg
tetracyclines, phenicols, fluroquinolones, 3rd and 4th generation cephalosporins.
Glycopeptides and bacitracin are only effective against...
Gram pos bacteria
Polymixins are effective against....
Only gram neg bacteria
Aminoglycosides and sulfonamides are effective against...
Nitroimidazoles are effective against...
What are the antibiotics classified into?
Inhibits cell wall synthesis, protein synthesis, membrane function, DNA/RNA synthesis, and various metabolic processes.
What is beta-lactams classified into?
Inhibits cell wall synthesis
List antibiotics that are beta-lactams
penicillin, cephalosporins, monobactams, carbapenems, glycopeptides, fosfomycins. *Have to have a cell wall unlike Mycoplasma and Ureaplasma*
What 2 amino acids form the beta-lactam ring?
Valine and Cysteine.