Anticoagulation & Thrombolysis

Question 1

Dabigtran

Answer 1

Anticoagulant: Direct thrombin inhibitor.

Question 2

Rivaroxaban (xarelto)

Answer 2

Anticoaglant: Xa inhibitor. Inactivates circulating Xa.

Question 3

Clopidogrel

Answer 3

Antiplatelet agent.

Question 4

Tx for venous thromboembolism in pregnant woman.

Answer 4

Low-molecular weight heparin or heparin.

Question 5

Contraindicated for anticoagulation in pregnancy.

Answer 5

Warfarin (Coumadin)- teratogen that causes fetal developmental disorders.

Question 6

Most common inherited hypercoagulability disorder that causes recurrent DVT’s.

Answer 6

Factor V Leiden

Question 7

Warfarin (Coumadin)

Answer 7

Inhibits vitamin K synthesis (factors II, VII, IX, X, protein C and S)

Question 8

Apixaban (Eliquis)

Answer 8

Factor Xa inhibitor.

Question 9

Aspirin (ASA)

Answer 9

Antiplatelet- prevents platelet aggregation

Question 10

Prasugrel

Answer 10

Antiplatelet agent

Question 11

1st-line Tx for DVT.

Answer 11

LMWH (Enoxaprin) or Warfarin (Coumadin)

Question 12

Low Molecular Weight Heparin (enoxaprin)

Answer 12

Accelerates antithrombin III and inhibits factors Xa and IIa