Special labs Flashcards
(27 cards)
Esophageal Cancer
SCC
Lung Cancer
CA-125, CEA, SCC
Liver Cancer
AFP
Gallbladder
CA 19-9, CEA
Prostate Cancer
PSA
Thyroid Medullary / Germ Cell Cancer
NSE
Breast Cancer
BRCA 1/2, with BRCA 1 more dominant in Ashkenazi Jewish population. Also CA-125
Gastric Cancer
CEA
Pancreatic Cancer
CA-125, CA 19-9 + increased pancreatic marker amylase and lipase.
Colon Cancer
CEA
Cervical Cancer
beta-HCG, SCC
Uterine Cancer
SCC, CA-125
Ovarian Cancer
beta-HCG, CA-125
Ankylosing Sprondylitis
HLA-B27
Rheumatoid Arthritis
Rheumatoid factor (RF) or anti-cyclic citrullinated peptide (Anti-CCP).
Systemic lupus erythematosus (SLE)
Antinuclear antibody (ANA), Anti-Sm antibody (more specific but not sensitive i.e not all with SLE have this. Every person with SLE has the ANA.
CREST syndrome (Scleroderma)
calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia
CREST/Scleroderma marker
Anti-centromere
Sjögren’s syndrome
Anti-Ro, Anti-La, SS-B
Gout
uric acid negative birefringent, needle like crystals
Psudogout
Calcium pyrophosphate positive birefringent, rhomboid shaped crystal
Scoliosis
Cobb angle >10 deg. Between 20 and 40 deg = back brace. >40 deg = surgery
Rhabdomyolysis
Elevated creatnine kinase (CK) after muscle damage or increase muscle demand (marathon runner) + dark urine + blood on urine dipstick with absent or minimal RBC’s.
Inflammatory arthritis of joint
Synovial fluid PMN’s >50%-70%, WBC 2000-10,000
