Antidepressants

Question 1

antidepressant onset and BBW

Answer 1

• delayed onset, won’t see full effect for about 3 weeks

- BBW: increased risk of suicidal thinking in pts. under 24 with depreassion or other psychiatric disorders

Question 2

dysthymia

Answer 2

chronic, low-grade depression

Question 3

anhedonia

Answer 3

inability to experience pleasure

Question 4

antidepressant classes (7)

Answer 4

triazolopyridines
tetracyclines
aminoketones
phenylpiperazines
selective serotonin and norepinephrine reuptake inhibitors
selective serotonin reuptake inhibitors
tricyclics

Question 5

triazolopyridines (1)

Answer 5

Oleptro

Question 6

Oleptro

Answer 6

trazodone ER tablet

• triazolopyridine
• ind. ONLY for depression: off-label use for insomnia)
• scored so OK to be cut, technology is Contramid
• tablet IR tablet is generic only: trazodone

Question 7

tetracyclines (2)

Answer 7

Remeron

Remeron SolTab

Question 8

Remeron

Answer 8

mirtazapine tablet

• tetracycline
• ind. ONLY for depression

Question 9

Remeron SolTab

Answer 9

mirtazapine ODT

• tetracycline
• ind. ONLY for depression

Question 10

aminoketones (3)

Answer 10

Wellbutrin
Wellbutrin SR
Wellbutrin XL

Question 11

Wellbutrin

Answer 11

bupropion

• aminoketone
• ind. for depression and SAD
• TID

Question 12

SAD

Answer 12

seasonal affective disorder

Question 13

Wellbutrin SR

Answer 13

bupropion

• aminoketone
• ind. for depression and SAD
• BID

Question 14

Wellbutrin XL

Answer 14

bupropion

• aminoketone
• ind. for depression and SAD
• qday

Question 15

Zyban

Answer 15

bupropion

• aminoketone
• ind. ONLY for smoking cessation

Question 16

nefazodone

Answer 16

• phenylpiperazine

- ind. ONLY for depression

Question 17

selective serotonin and norepinephrine reuptake inhibitors (4)

Answer 17

-SNRIs
-raise serotonin and NE levels in the brain
Effexor
Pristiq
Cymbalta
Savella

Question 18

Effexor

Answer 18

venlafaxine

• SNRIs
• ind. for depression, anxiety, and panic disorder

Question 19

Pristiq

Answer 19

desvenlafaxine

• SNRIs
• ind. ONLY for depression
• active metabolite of venlafaxine

Question 20

Cymbalta

Answer 20

duloxetine

• SNRIs
• ind. for depression, anxiety, fibromyalgia, DPN, and chronic musculoskeletal pain

Question 21

Savella

Answer 21

milnacipran

• SNRIs
• ind. ONLY for fibromyalgia

Question 22

selective serotonin reuptake inhibitors (7)

Answer 22

-SSRIs
-raise serotonin levels
Prozac
Paxil
Pexeva
Zoloft
Luvox CR
Celexa
Lexapro

Question 23

SSRIs ind. as a class (6)

Answer 23

depression
OCD
anxiety
panic disorder
PTSD
PMDD

Question 24

Prozac

Answer 24

fluoxetine

-SSRI

Question 25

Paxil

Answer 25

paroxetine HCl | -SSRI

Question 26

Pexeva

Answer 26

paroxetine mesylate - SSRI - cannot be switched with Paxil because they are different salt forms

Question 27

Zoloft

Answer 27

sertraline | -SSRI

Question 28

Luvox CR

Answer 28

fluvoxamine - SSRI - ind. ONLY for OCD, does NOT treat depression

Question 29

Celexa

Answer 29

citalopram - SSRI - racemic

Question 30

drugs ind. for PMDD

Answer 30

fluoxetine sertraline Paxil Yaz (drospirenone, ethinyl estradiol)

Question 31

tricyclics (6)

Answer 31

``` pt. counseling: may cause drowsiness, avoid alcohol, use good dental care, may cause dry mouth amitryptyline Anafranil doxepin Norpramin Tofranil Pamelor ```

Question 32

amitriptyline

Answer 32

-tricyclic

Question 33

Anafranil

Answer 33

clomipramine - tricyclic - ind. ONLY for OCD - SE: 5% of people have orgasm when yawn

Question 34

doxepin

Answer 34

- tricyclic | - ind. ONLY for insomnia

Question 35

Norpramine

Answer 35

desipramine | -tricyclic

Question 36

Tofranil

Answer 36

imipramine | -tricyclic

Question 37

Pamelor

Answer 37

nortriptyline | -tricyclic

Question 38

Evoxac, Salagen

Answer 38

- cholinergic agents - ind. for xerostomia and Tx of Sjogren's Syndrome symptoms - autoimmune disease often in elderly women that can dry mucus membranes and cause xerostomia

Question 39

Lexapro

Answer 39

escitalopram - SSRI - only contains the "S" isomer