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Flashcards in antidepressants Deck (6):
1

Imiprazine

Class: TCA (tertiary amine)
Mechanism: NE/5-HT uptake
Side Effects: arrhythmias, av block, orthostatic hypotension

2

Desipramine

Class: TCA (secondary amine)
Mechanism: NE uptake
Side Effects: arrhythmias, av block, orthostatic intolerance

3

Fluoxetine

Class: SSRI
Mechanism: 5-HT uptake
Side Effects: Nausea, vomiting, sexual dysfunction, asthenia

4

venlafaxine

Class: SNRI
Mechanism: low dose NE uptake, high dose NE/5HT uptake
Side Effects: nausea vomiting, sexual dysfunction, asthenia

5

Phenelzine

Class: MAOI
Mechanism: irreversible MAO inhibition
Side Effects: hepatotoxicity, CNS, orthostatic hypotension, Cheese Rxn hypertensive crisis (tyramine)

6

Mirtazapine

Class: not classified
Mechanism: alpha-2 adrenoceptor blockade
Side Effects: weight gain