Antiemetic Agents - Scopolamine Flashcards
(15 cards)
What is the typical dosage of transdermal scopolamine for motion sickness or PONV?
0.5 mg patch applied every 72 hours
This dosage is standard for preventing nausea and vomiting.
What is the mechanism of action of Scopolamine?
Muscarinic receptor antagonist
It blocks the action of acetylcholine at muscarinic receptors.
Which of the following is a clinical effect of Scopolamine?
Sedation and antiemesis
These effects are beneficial in managing nausea and inducing calm in patients.
How long does the transdermal scopolamine patch typically last?
72 hours
This duration allows for extended relief from symptoms.
In which patient scenario is scopolamine most appropriately used?
A patient undergoing surgery with high risk for PONV
This is a common indication for its use in the perioperative setting.
Does Scopolamine enhance acetylcholine activity in the CNS?
No
It actually inhibits acetylcholine activity.
Can Scopolamine cause dry mouth, blurred vision, and confusion as side effects?
Yes
These are common anticholinergic side effects.
Is Scopolamine commonly used to reduce secretions and prevent motion sickness?
Yes
It is effective for both indications.
Is Scopolamine a dopamine receptor blocker?
No
It primarily acts on muscarinic receptors, not dopamine receptors.
Is the onset of action of transdermal scopolamine immediate after patch application?
No (It typically takes 4–6 hours for full effect.)
Patients should be advised to apply the patch ahead of time.
What is the primary clinical use of scopolamine in anesthesia?
Prevention of postoperative nausea and vomiting (PONV) and reduction of secretions
It is a key medication in managing these issues in surgical patients.
List two common side effects of scopolamine.
Dry mouth and drowsiness.
Other side effects can include blurred vision, confusion, and urinary retention.
What is the onset time of a transdermal scopolamine patch?
Approximately 4–6 hours
This delay should be considered in clinical settings.
How long does the effect of a scopolamine patch last?
Up to 72 hours.
This allows for sustained symptom management.
Describe the mechanism of action of scopolamine.
It is a competitive antagonist at muscarinic acetylcholine receptors, inhibiting parasympathetic nerve impulses.
This action helps in reducing nausea and secretions.
