Antifungals Flashcards Preview

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Flashcards in Antifungals Deck (14):
1

interferes w/ microtubule fxn

grizeofulvin

2

swish and swallow for oral candidiasis

nystatin

3

cell wall synth inn used for invasive aspergillosis

caspofungin

4

binds ergosterol --> membrane pores

amphotericin B and nystatin

5

Inh ergosterol synthesis

azoles, terbinefine

6

MC tx for onychomycosis

terbinafine and itraconazole

7

arrythmias and nephrotoxidicy

amphotericin B

8

deposits in keratin containing tissues

griseofulvin

9

inhibits hormone synthesis and CYP450

azoles

10

liver dysfxn

azoles and grizeofulvin

11

teratogenic

grizeofulvin

12

used for cryptococcal meningitis in aids pts

IV amphotericin B and flucytosine

13

converted to fluorouracil and inhibits DNA synth

flucytosine

14

Drugs of choice for sporotrichosis

itraconazole