Antihypertensives Flashcards

(47 cards)

1
Q

This drug acts on the vasomotor center

A

METHYLDOPA
and Clonidine

Sympathoplegics (Centrally-Acting)

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2
Q

Acts on the vascular smooth muscle

A

Hydralazine

vasodilator

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3
Q

AliskeREN

A

Direcet RENin Inhibitor

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4
Q

Captopril

A

ACE Inhibitor

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5
Q

Losartan

A

ARB

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6
Q

Hydrochlorothiazide

A

Diuretics. Thiazide.

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7
Q

Direct Renin Inhibitor

A

Aliskeren

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8
Q

Benzothiazepine calcium channel blocker

A

diltiazem

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9
Q

NOT a vasodilator

a. hydralazine
b. minoxidil
c. diazoxide
d. methyldopa

A

methydopa

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10
Q

All BUT one is not a parenteral vasodilator agents

a. amlodipine
b. Na nitroprusside
c. fenoldepam
d. labetalol

A

a. amlodipine

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11
Q

selective beta blocker that stimulates the

RELEASE OF NO CAUSING VASODILATION

A

Nevibolol

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12
Q

NON SELECTIVE beta blocker

A

Propranolol

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13
Q

DOC for

uncontrolled hypertension and recurrent bipedal edema and orthopnea

A

hydrochlorothiazide

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14
Q

DOC for

hypertension and DIABETES

A

valsartan

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15
Q

DOC for

hypertension and ANGINA

A

nevibolol

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16
Q

DOC for
hypertension, atrial fibrillation (S/Sx ng thyrotoxicosis)
and THYROTOXICOSIS

A

Propranolol

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17
Q

DOC for

buntis with hypertensive

A

Methyldopa

and Clonidine

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18
Q

blocks Na/Cl transporter in the

DISTAL convoluted tubule

A

thiazide

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19
Q

blocks Na/Cl transporter in the

COLLECTING tubule

A

Spirinolactone

20
Q

blocks Na/Cl transporter in the

PROXIMAL convoluted tubule

A

Acetazolamide

21
Q

blocks Na/Cl transporter in the

renal LOOP OF HENLE

22
Q

blocks vesicular amine transporter in noradrenergic nerves and depletes transmitter stores

A

reserpine

and guanethidine

23
Q

Selectively blocks apha-1 adrenoceptors

A

Prazosin,

saka Terazosin, Doxazosin

24
Q

most common side effect of ACE inhibitors

25
teratogenicity is NOT a side effect of
Clonidine ...saka methyldopa
26
Angioedema is NOT seen as a side effect of
Thiazide
27
Angioedema is seen as a side effect of
Amlodipine Lisinopril Nifedipine
28
Side effect: Hypertrichosis
Minoxidil
29
Side effect: Hemolytic anemia
Methyldopa
30
Severe neutropenia or proteinuria if given in high doses in patients with renal insufficiency
Captopril
31
should not be combined with ARBs
Lisinopril (ACE inhibitors)
32
should not be given to patient with hypertension having bronchial asthma
Propanolol (kasi non-selective, need ng asthmatic ng B2 agonist)
33
Contraindication: heart block
Metoprolol
34
Contraindication: Glaucoma
Fenoldepam (increases intraocular pressure)
35
Diuretics
Thiazides: Hydrochlorothiazide, Chlorthalidone Loop diuretics: Furosemide Spironolactone, Eplerenone
36
Potassium-sparing diuretics: | Diuretic with increased Na and decresed K excretion
Spirinolactone saka Amiloride also, Epleneron and Triamterene
37
Potassium-sparing diuretics contraindicated in patients with:
renal insufficiency
38
Only THIAZIDE available for PARENTERAL administration
Chlorothiazide
39
Diuretic. side effectL Ototoxicity
Loop diuretic (Furosemide)
40
competitive inhibitor of RENin
aliskiREN
41
Clonidine side effect:
sedation
42
activate alpha-2 adrenoceptors
Clonidine, | methyldopa
43
vasodilators
``` hydralazine, minoxidil diazoxide (parenteral agent) verapamil diltiazem mifedipine amlodipine fenoldopam (parenteral agent) nitroprusside (parenteral agent) labetalol (parenteral agent) ```
44
parenteral vasodilator agents
diazoxide (parenteral agent) fenoldopam (parenteral agent) nitroprusside (parenteral agent) labetalol (parenteral agent)
45
very widely used Beta-1 selective blockers
Metoprolol | Atenolol
46
Also treats hair loss
Minoxidil
47
Hydralazine side effect:
Lupus-like syndrome, angina, tachydardia