Antihypertensives Medchem Flashcards

1
Q

Bradykinin not broken down

A

Higher levels of bradykinin particularly in lungs

Dry cough

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2
Q

Allostery of CCB

Verapamil

Diltiazem

1,4 -dihydropyridines

A

Verapamil + Diltiazem = NEGATIVE allosteric effect

Diltiazem + 1,4-dihydropyridines = POSITIVE allosteric effect

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