Psoriasis Flashcards
1
Q
Atopic dermatitis - Common among?
A
Children
2
Q
Psoriasis treatment 1st line?
A
- Layer treatment:
- emollient
- vitD analogues
- topical corticosteroids
- dithranol
- coal Tae
3
Q
Psoriasis second line treatment?
A
- UVB & PUVA
- systemic non-biological agents eg.
- MTX, ciclosporin, acitretin
4
Q
Psoriasis third line treatment ?
A
• systemic biological agents
5
Q
Emolient: cream & ointment in psoriasis?
A
- sooth, smooth, hydrate
- apply regularly & liberally
- soap substitute
- bath/shower emollient
6
Q
Cream vs ointment emolient?
A
- ointment slippery, better to prevent evaporation esp overnight
- cream looks absorbed but aesthetic
7
Q
Psoriasis triggers?
A
- Infections
- weather
- skin injury
- smoking & passive
- heavy alcohol
8
Q
Psoriasis is…?
appearance?
A
- a skin condition that causes flaky patches of skin which form scales.
- pink or red patches
- scales - white or silver
- brown & black skin
- patches purple or dark brown
- scales - grey
9
Q
VitD analogues in psoriasis pharmacology?
A
- inhibit Tcell activation
- inhibit maturation of karatinocytes thus epidermal cells
- intefere with cytokine release
- cream & ointment - OD or BD
10
Q
Topical corticosteroid?
A
- inappropriate for widespread psoriasis
- cant use long term. max. 8 weeks.
• anti-inflammatory & antiproliferative
11
Q
Dithranol in psoriasis?
A
- anti-proliferative
- v. irritant
- apply with brush on top of white soft paraffin.
- avoid on healthy skin
- stains skin, clothing
- not for acutely inflamed psoriasis.
12
Q
Symptomatic treatment in psoriasis treats?
A
- remove scale
- remove over production of cells
- reduce inflammation
- improve maturation & hydrate cells.
