antihypertensives PG 882 Flashcards

(27 cards)

1
Q

what is considered normal blood pressure

A

<120/<80

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2
Q

what is considered elevated blood pressure

A

120-129/80

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3
Q

what is considered stage 1 hypertension

A

130-139/80-89

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4
Q

what is considered stage 2 hypertension

A

> 140/>90

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5
Q

what is step 1 of treating hypertension

A

lifestyle changes

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6
Q

what is stage 2 of treating hypertension

A

thiazide diuretic, ACE inhibitor, ARB, or CCB (use 1)

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7
Q

consider using which type of medication in African American patients due to increased risk of angioedema

A

use ARB instead of ACE inhibitor

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8
Q

what is stage 3 of treating hypertension

A

increase dose of drugs or combine two drugs

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9
Q

what is step 4 of treating hypertension

A

combine 2-3 of step 3

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10
Q

what are the different classes of antihypertensive medication

A

ACE inhibitors/angiotensin II antagonists (ARBs)
diuretics
calcium channel blockers
beta blockers

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11
Q

action of ACE inhibitors

A

lower BP by dilating arterial blood vessels

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12
Q

what medication is used in first line treatment of HTN in patients with DM

A

ACE inhibitors

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13
Q

adverse effects of ACE inhibitors

A

postural/orthostatic hypotension
angioedema (in african american patients)
dry hacking cough

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14
Q

contraindications of ACE inhibitors

A

renal or hepatic disease

electrolyte imbalance

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15
Q

action of calcium channel blockers

A

causes peripheral vasodilation

inhibits calcium from getting in to muscle cells to cause contraction

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16
Q

what are the 2 categories of calcium channel blockers

A

dihydropyridines - little to no negative effect on cardiac contractility or conduction

non-dihydropyridines - greater depressive effect on cardiac conduction and contractility

17
Q

adverse effects of dihydropyridines

A

headache, lightheadedness, flushing, peripheral edema

18
Q

adverse effects of non-dihydropyridines

A

constipation, bradycardia, heart failure, heart block

19
Q

contraindications of dihydropyridines

A

hepatic impairment, severe coronary artery disease, and sever aortic stenosis

20
Q

contraindications of non-dihydropyridines

A

second or third degree heart block, acute MI, congestive heart failure

21
Q

action of beta blockers

A

compete with adrenergic neurotransmitters (epi and norepi) for adrenergic receptor sites

22
Q

where are beta1 receptor sites usually located

23
Q

where are beta2 receptors usually located

A

bronchial and vascular smooth muscle and the uterus

24
Q

which beta receptors do selective beta blockers work on

25
which beta receptors do non selective beta blockers work on
beta1 and beta2
26
adverse effects of beta blockers
orthostatic hypotension, bradycardia, bronchospasm
27
contraindications of beta blockers
sinus bradycardia, heart block, hypotension