antimicrobial drug (1)

Question 1

The use of drugs to treat a disease

Answer 1

Chemotherapy

Question 2

these drugs Interfere with the growth of microbes within a host.

Answer 2

Antimicrobial drugs

Question 3

Produced by a microbe, inhibits other microbes.

Answer 3

Antibiotic

Question 4

Who developed Salvarsan (Arsphenamine) againts syphilis in 1910

Answer 4

Paul Eherlich and Sahachiro Hata

Question 5

sulfa drugs ( sulfanilamide ) were discovered in _____ againts __________

Answer 5

• 1932
• Gram positive bacteria

Question 6

who discovered penicillin

Answer 6

Fleming in 1928

Question 7

Who were the first to perform first clinical trials of penicilin

Answer 7

Howard and Ernst Chain

Question 8

Drug kills pathogens without damaging the host

Answer 8

Selective toxicity

Question 9

ratio between toxic dose and therapeutic dose

Answer 9

Therapeutic index

Question 10

High therapeutic index = ?

Answer 10

Less toxic

Question 11

Inhibits the growth and reproduction of bacteria

Answer 11

Bacteriostatic

Question 12

Kills bacteria directly

Answer 12

Bactericidal

Question 13

4 ACTION OF ANTIMICROBIAL DRUGS

Answer 13

1. Inhibit on of cell wall synthesis
2. Inhibition of protein synthesis
3. Injury to plasma membrane
4. Inhibition of synthesis of essential metabolites