Antimicrobial Pharmacology session 1 Flashcards

(48 cards)

1
Q

Prontosil is against which organisms?

A

strep and staph

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2
Q

What does Prontosil make in the body?

A

sulfonamide

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3
Q

What sulfonamide does?

A

prevent the synthesis of folic acid in bacteries

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4
Q

What do we use for chronic prostatitis?

A

fluoroquinolone

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5
Q

Optimum concentration

A

4 times more than the standard amount

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6
Q

MIC

A

minimum inhibitory concentration

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7
Q

MBC

A

minimum bactericidal concentration

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8
Q

strip or targigi?

A

strip is better because the amounts are closer and the results are better

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9
Q

معیار اصلی در دسته بندی آنتی بیوتیک ها

A

ساختاری که دارو در باکتری به آن اثر می گذارد

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10
Q

Antibiotics that affect the folic acid synthesis

A

trimethoprim

sulfonamide

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11
Q

Antibiotics that affect 50S protein synthesis

A

erythromycin
chloramphenicol
clindamycin

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12
Q

Antibiotics that affect 30S protein synthesis

A
tetracycline
spectinomycin
streptomycin
gentamycin
tobramycin
amikacin
aminoglycosides
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13
Q

Antibiotics that affect DNA and RNA

A

quinolone

rifampin

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14
Q

drugs that avoid cell wall synthesis are?

A

bactericide

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15
Q

vancomycin is?

A

glycopeptide

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16
Q

Telavancin is made up of?

A

vancomycin

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17
Q

Dalbavancin is made up of?

A

teicoplanin

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18
Q

Colistin

A

has lots of side effects but is used for some severe cases

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19
Q

Cell-membrane related drugs

A

daptomycin and polymyxin

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20
Q

aplastic anemia

A

chloramphenicol

21
Q

جایگزینی به جای تتراسایکلین در باردارها

A

chloramphenicol

22
Q

دارویی با طیف گسترده و باکترواستاتیک

23
Q

دارویی با طف گسترده و باکتریوساید

24
Q

Clindamycin is effective on?

A

gram-positive non-O2

25
Drugs in the group of macrolides
erythromycin clarithromycin azithromycin spiramycin
26
anti-inflammation effects?
azithromycin
27
To treat toxoplasmosis in pregnancy
spiramycin
28
To treat helicobacter pylori
clarithromycin
29
Aminoglycosides are effective on?
gram-negative and O2
30
how can we use aminoglycosides for gram positives?
with B-lactams
31
سوزاک؟
spectinomycin (only used for these cases)
32
The main treatment of Gonorrhea?
B-lactams but for replacement, we use spectinomycin
33
Streptogramins?
quinupristin and dalfopristin
34
Treatment of penicillin-resistant streptococci pneumonia & vancomycin-resistant staph
Linezolid
35
Protein synthesis inhibitor but uses tRna
Mupirocin
36
Drugs that affect nucleic acids
rifamycin fluoroquinolone rifaximin fidaxomicin
37
موثر بر سل و جذام و عفونت شدید استاف و درمان مننژیت و بروسلوز؟
Rifampin
38
Treatment of chronic prostatitis
fluoroquinolone
39
درمان اسهال مسافرتی
rifaximin | در روده به مدت طولانی باقی می ماند
40
Antimetabolites
``` sulfonamide (bacteriostatic) trimethoprim pyrimethamine proguanil methotrexate ```
41
To treat toxoplasma ghondi
sulfadiazine with pyrimethamine
42
Only effective on human reductase
Methotrexate
43
Metronidazole
non-O2 and single cells
44
Reasons we use antibiotics
prophylaxis | treat
45
Empirical
give drugs for a variety of infections
46
definitive
give drug for specific type of infection
47
درمان پنومونی اکتسابی از جامعه
levofloxacin
48
درمان پیلونفریت
ceftriaxone