Antimicrobial Pharmacology Session 4 Flashcards

(53 cards)

1
Q

Aminoglycosides

A
Streptomycin
Neomycin
Kanamycin
Paromomycin
Tobramycin
Gentamicin
Amikacin
Spectibomycin
Netilmicin
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2
Q

خط اول دفاعی در برابر سل

A

Streptomycin

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3
Q

درمان‌های موثر بر سل

A

Streptomycin + kanamycin

Imipenem + clavulanic acid

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4
Q

Alternative for ceftriaxone for گونوکوک

A

Spectinomycin

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5
Q

طیف اثر آمینوگلیکوزید

A

موثر بر گرم‌منفی‌های هوازی

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6
Q

Synergistic relation between?

A

Aminoglycosides and antibiotics

Vancomycin and penicillin

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7
Q

Aminoglycosides mechanisms to inhibit protein synthesise

A

Block protein synthesise
مهار تداوم پروتئین سازی
Miscoding

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8
Q

Which drug doesn’t have miscoding?

A

Spectinomycin

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9
Q

Resistance to aminoglycosides mechanisms?

A

Inactivation of enzymes
Decrease diffusion of antibiotics
تغییر تمایل اتصال

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10
Q

Full cross resistance

A

Kanamycin & neomycin

Netilmicin, kanamycin, tobramycin, gentamicin, amikacin

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11
Q

Diffusion problems of aminoglycosides

A

Diffuse to kidney and has nephrotoxicity

Diffuse to endolymph and perilymph

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12
Q

2 important features of aminoglycosides

A

Post-antibiotical

Amount related

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13
Q

Patients that cannot use single dose aminoglycosides

A

Pregnants
Kidney injury
Infants
Endocarditis

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14
Q

استریل روده قبل جراحی

A

Neomycin

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15
Q

پیشگیری از کمای هپاتیک یا انسفالوپاتی کبدی

A

Neomycin

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16
Q

درمان آمیبیازیس

A

Paromomycin

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17
Q

عفونت‌های جلدی ناشی از گرم منفی

A

‌neomycin

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18
Q

لشمانیوز احشایی

A

Paromomycin تزریقی

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19
Q

لشمانیوز پوستی و تریکوموناس

A

Paromomycin موضعی

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20
Q

ژیاردیازیس‌های دوره بارداری

A

استفاده از paromomycin خوراکی به جای metronidazole

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21
Q

تولارمی یا تب خرگوشی

A

Gentamicin and streptomycin

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22
Q

طاعون

A

Streptomycin & tetracycline

23
Q

سودوموناس (پنومونی یا باکتریمی)

A

Broad spectrum penicillin
+
Tobramycin and cefdazidim

24
Q

برسلوز یا تب مالت

A

Doxycycline and gentamicin

Doxycycline and rifampin

25
اتدوکاردیت و باکتریمی استرپتوکوکی
Gentamicin + penicillin G
26
Treatment of enteroco
Ampicillin OR penicillin G Both with gentamicin Or vancomycin + gentamicin [Vancomycin allergic] Linezolid and quinupristin-dalfopristine [Vancomycin resistant]
27
درمان گنوره
Spectinomycin
28
Highest and lowest kidney injury causes of aminoglycosides
Neomycin | Streptomycin
29
آسیب شنوایی آسیب تعادلی
Amikacin and kanamycin Gentamicin and streptomycin
30
Contraceptions aminoglycosides
B-lactam and aminoglycosides Diuretic and hearing Warfarin and خونریزی آمینوگلیکوزید در دوران شیردهی آمینوگلیکوزید در دوران بارداری
31
Groups of tetracyclines
Natural: demeclocycline and tetracycline Semisynthetic: doxycycline
32
Treatment of unusual secretion of ADH
Demeclocycline | Lithium carbonate
33
Treatment of H. Pylori
Tetracycline +chloromycetin
34
Resistance mechanisms to tetracycline
Decrease accumulation of tetracycline Decrease approach to tetracycline Enzymatic inactivation
35
We can't use tetracyclines with?
دو یا سه ظرفیتی‌ها
36
حساس به شیر و دوغ
Tetracycline
37
Tetracyclines are mostly found in?
High calcium turnover | Liver
38
درمان تب مالت
Long use of doxycycline (2-3 months)
39
Disposal of minoxycline and doxycycline
Liver
40
درمان آکنه‌های مقاوم به درمان موضعی
Tetracycline
41
درمان وبا در زیر ۸ سال
Tetracycline ❌️ | Azitromycin
42
Treatment of ricketssia
Doxycycline If not: chloramphenicol
43
عامل و درمان بیماری لایم
بورلیا Doxycycline
44
Alternative drugs for macrolides
Doxycyclines
45
Treatment for leptospira and treponema
B-lactams Alternative: doxycycline
46
Treatment for borrelia
Doxycycline Alternative: B-lactams
47
آلترناتیو درمان سیفیلیس حساس به پنی‌سیلین
Doxycycline
48
درمان ترشح نامناسب ADH
Demeclocycline and lithium carbonate
49
Contraindications of tetracycline
``` دو یا سه ظرفیتی‌ها Cholestyramine (inhibits cholesterol) Sucralfate (aluminium) پنی‌سیلین OCPs Digoxin Alcohol Warfarin ```
50
ضد تشنج‌ها
Phenobarbital | Phenytoin
51
Side effects of tetracyclines
``` تهوع استفراغ اسهال بی‌اشتهایی زخم مری فوبیای نور دیابت نفروژنیک ندروم شبه فانکونی ```
52
داروی درمانی در عفونت‌های داخل شکمی
Tigecycline
53
Most common side effect of tygecycline
تهوع و استفراغ