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ENGR 1 > Antimicrobials > Flashcards

Antimicrobials Flashcards

1
Q

Doxycycline

A

non-renally eliminated tetracycline

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2
Q

Quinolones

A

ciprofloxacin is renally eliminated but is a non-substrate inhibitor of P450 (caffeine-theophylline)

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3
Q

Clindamycin

A

non-renally eliminated

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4
Q

Rifampin

A

inducer of P450, potential for hepatotoxicity

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5
Q

Isoniazid

A

genetic polymorphism of N-acetyl transferase metabolism, potential for hepatotoxicity

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6
Q

Metronidazole

A

drug-drug interaction with alcohol due to inhibition of aldehyde metabolism (Antabuse reaction)

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7
Q

Erythromycin-like

A

drug-drug interactions due to inhibition of P450 (Clar-Ery not Azi)

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8
Q

Sulfonamides

A

N-acetylated to a more lipid-soluble metabolite → concern for renal crystalluria

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9
Q

Gram positive cocci

A 
strep pneumo
strep pyogenes
strep viridans
staph aureus (MSSA-MRSA)
enterococcus faecium-fecalis
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10
Q

gram negative cocci

A

n. gonorrhea

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11
Q

gram positive rod

A

NONE

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12
Q

gram negative rod

A

e coli
h nfluenza
klebsiella
pseudomonas aeruginosa

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13
Q

anaerobe- gram positive rod

A

c diff
c perfringens
c botulinum
c tetani

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14
Q

anaerobe- gram negative rod

A

bacteroides fragilis

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15
Q

atypical

A

chlamydia

mycoplasma pneumoniae

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16
Q

strep pneumo

A

pneumonia
otitis media
sinusitis

17
Q

strep pyogenes

A

pharyngitis

18
Q

strep viridans

A

endocarditis

19
Q

staph aureus

A

cutaneous infection
pneumonia
bacteremia
device assoc infections

20
Q

enteroccocus faecium-fecalis

A

bacteremia
intraabdominal infection
UTI

21
Q

gonorrhea

A

gonorrhea

22
Q

e coli

A 
UTI
intraabdominal infection
lower respiratory infection
bacteremia
traveler's diarrhea
23
Q

h influenza

A

meningitis
otitis media
sinusitis
community acquired pneumonia

24
Q

klebsiella

A

UTI
intraabdominal infection
lower respiratory infection
bacteremia

25
Q

pseudimonas aeruginosa

A

nosocomial infections (UTI/pneumonia)

26
Q

c diff

A

pseudomembranous colitis

27
Q

bacteroides fragilis

A

intraabdominal

brain abscess

28
Q

chlamydia

A

trachoma
community acquired pneumonia
urethritis

29
Q

mycoplasma pneumonia

A

community acquired pneumonia

30
Q

Drugs-Drug Classes eliminated by renal excretion requiring dosage adjustments if renal impairment

A 
Penicillins - 
Cephalosporins-
Vancomycin-
Aminoglycosides-
Fluoroquinolones

ENGR 1 (29 decks)

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