Antimicrobials: Selective Toxicity Flashcards Preview

Infectious Disease: Unit 1 > Antimicrobials: Selective Toxicity > Flashcards

Flashcards in Antimicrobials: Selective Toxicity Deck (12)
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1
Q

Prototypical Penicillins

A

Humans don’t have cell walls

2
Q

Cephalosporins: Penicillinase resistant

A

Humans don’t have cell walls

3
Q

Carbapenems. Beta lactamase resistant.

A

Humans don’t have cell walls

4
Q

Monobactams

A

Humans don’t have cell walls

5
Q

Vancomycin

A

Humans don’t have cell walls

6
Q

Macrolides

A

Humans don’t have 50S

7
Q

Tetracylines

A

Humans don’t have 30S

8
Q

Metronidazole

A

Active on organisms performing anaerobic respiration

9
Q

Fluoroquinolones

A

Humans don’t have DNA gyrase, we supercoil in other ways

10
Q

Sulfonamides

A

Humans get Folic Acid from diet, don’t have to synthesize it for DNA. Also, humans lack DHPS enzyme

11
Q

Nitrofurantoin

A

Mamillian enzymes don’t reduce it as rapidly

12
Q

Antituberculuar Agents (Rifampin)

A

Bacteria have different RNA polymerase