Antimuscarinics Flashcards
(6 cards)
1
Q
Antimuscarinics examples
A
Oxybutynin
Darifenacin
Solifenacin
Tolterodine
2
Q
MOA of antimuscarinics
A
Inhibit the muscarinic action of acetylcholine on the smooth muscle, therefore relaxing the bladder which increases the urinary capacity
3
Q
Antimuscarinics CI
A
Severe UC
Significant bladder outflow obstruction
Toxic megacolon
Urinary retention
4
Q
Antimuscarinics caution
A
Acute MI
Arrhythmia
Congestive HF
HTN
Hyperthyroidism
UC
5
Q
Antimuscarinics in elderly
A
2 or more together increases risk of antimuscarinic toxicity
Risk of exacerbating cognate impairment in dementia
6
Q
Antimuscarinics SE
A
Constipation
Dizziness
Drowsiness
Dry mouth
Dyspepsia
Palpatations
Confusion
