PPI

Question 1

Risks with PPI

Answer 1

Mask gastric cancer
Increase risk of fractures (particularly in high doses and elderly)
Increase risk of GI infections (cdiff)

Question 2

MHRA PPI

Answer 2

Subacute cutaneous lupus erthematosus can occur weeks, months and even years later

Question 3

Monitoring requirement for PPI

Answer 3

Magnesium as can cause hypomagnesaemai

Question 4

Increased risk of osteoporosis and PPI

Answer 4

Maintain intake of calcium and vit d