Antimycotics

Question 1

Onychomycosis

Answer 1

Terbinafine
Intraconazole

Question 2

Cryptococcal meningitis

Answer 2

Flucanozole
Amphoteracin B

Question 3

Oropharyngeal candidiasis

Answer 3

Nystatin
Fluconazole

Question 4

Invasive Aspergillosis

Answer 4

Vornicazole

Question 5

Mucomycosis

Answer 5

Isacuvonazole

Question 6

Tinea Versicolor

Answer 6

Ketaconazole

Question 7

Antimycotic that inhibits alpha demethylase causing a decrease in ergosterol

Answer 7

Azoles

Question 8

Antimycotic that bind to egosterol forming pores

Answer 8

Polyenes

Question 9

Terbinafine MOA

Answer 9

inhibition of squalene causing a decrease of ergosterol

Question 10

MOA of Caspofungin

Answer 10

Inhibits beta glucan

Question 11

Antimycotic that can cause reversible alopecia

Answer 11

Fluconazole

Question 12

Azole to most commonly cause Hepatoxicity

Answer 12

Itraconazole

Question 13

Other functions of Ketoconzole

Answer 13

Prostate cancer
Psoriasis
Hypercotisolism
Hurtism

Question 14

Azole that May cause adrenal Cortez insufficiency

Answer 14

Ketaconazole

Question 15

Indications of Miconazole

Answer 15

Topical fungical infections
- vaginal candidiasis
- Tinea versicolor

Oropharyngeal candidiasis

Question 16

Drug of choice for Histoplasmosis

Answer 16

Itraconazole

Question 17

Drug of choice for Blastomycosis

Answer 17

Itraconazole

Question 18

Px that after visit to a bat cave starts with a fungal infection, which Antimycotic do you use?

Answer 18

Itraconazole
(Coccidomycosis)

Question 19

Antimycotic that can lead to fatal cardiac arrhythmias if combined with malaria tx and heroin addiction Tx

Answer 19

Itraconazole

Question 20

T or F: Fluconazole has greater spectrum than Itraconazole

Answer 20

F

Question 21

Onychomycosis Antimycotic that is contradicted in pregnant women

Answer 21

Itraconazole

Question 22

Antimycotic used for salvage therapy vs Aspergillosis

Answer 22

Caspofungin
Posaconazole

Question 23

Azole related to cause visual disorders ( photosensitivity and blurry vision)

Answer 23

Vornicazole

Question 24

Adverse effects caused by the systemic use of azoles

Answer 24

Hepatotoxic
GI upset
QT prolongation
Hypokalemia
Gynecomastia

Question 25

Contraindications for Azole use

Answer 25

Cardiac arrhythmias Severe cardiac insufiency PPIs ( Azoles requiere low ph to be absorbed)

Question 26

Antimycotic that can cause Stevens-Johnson’s Syndorme

Answer 26

Fluconazole Nystatin Terbinafine

Question 27

Adverse effects of Amphoteracin B

Answer 27

Nephrotoxicity Arrythmias IV phlebitis “Shake and bake” = fever and chills

Question 28

Antimycotic that causes fever and chills (shake and bake)

Answer 28

Amphoteracin B

Question 29

Dermatophysis or “Ringworm”

Answer 29

Ketoconazole (Athletes foot)

Question 30

T or F: Nystatin only is active vs. Cándida

Answer 30

T

Question 31

What is the only indication of Keroconazole

Answer 31

Candidiasis

Question 32

Antimycotic drug that causes flushing

Answer 32

Caspofungin