antiprotozoal

Question 1

dystentery caused byintestinal invasion of the trophozoite tsage of protozoan entamomeba histolytica

Answer 1

amebiasis

Question 2

type of mosquito that is essential to the life of plasmodium, inject protozoa into humans for further maturation

Answer 2

anopheles mosquito

Question 3

syndrome of quinine toxocity characterized by nausea, vomitting, tinnitus, vertigo

Answer 3

chichonism

Question 4

protozoal intestinal infection that causes severe diarrhea and epigastric distress, may lead to serious malnutrition

Answer 4

giardiasis

Question 5

skin, mucous memebrane, or visceral infection caused by protozoan passed by humans by the bites of sand flies

Answer 5

leishmaniasis

Question 6

protozoal infection with plasmodium, characterized by cycllic fever and chills as the parasite is released from rupture red blood cells, causes serious liver, cns, heart and lung damage

Answer 6

malaria

Question 7

protozoan that causes malaria to humans

Answer 7

plasmodium

Question 8

oppurtunistic infection that occurs when the immune system is depressed, a frequent cause of pneumonia in patient with AIDS and in those who are receiving immunosupressive therapy

Answer 8

pneumocystis jiroveci pneumonia

Question 9

single celled organism that pass through several stages in thier life cycle, including atleast one phase as a human parasite

Answer 9

protozoa

Question 10

found on areas with poor sanitatin hygiene, crowded living condition

Answer 10

protozoa

Question 11

infestation with protozoan that causes vaginitis in women but no sign and syntoms for men

Answer 11

trichomoniasis

Question 12

a developing stage of parasite, which uses the host for essential nutrients needed for growth

Answer 12

trophozoite

Question 13

african-sleeping sickness, which is caused by protozoan that inflames the CNS and is spread to humans by the bite of tseste fly

Answer 13

trypanosomiasis

Question 14

african-sleeping sickness is caused by a fly called

Answer 14

tseste fly

Question 15

chaga’s disease is caused by a fly called

Answer 15

house fly

Question 16

drugs for antimalaria (ppqcm)

Answer 16

primaquine
pyrimethamine
quinine
chloroquine
mefloquine

Question 17

drugs for other antiprotozoal (manpt)

Answer 17

metronidazole
atovaquone
nitazoxanide
pentamidine
tinidazole

Question 18

informal termed for a single celled eukaryotes

Answer 18

protozoa

Question 19

one celled organism like bacteria, but they are bigger than bacteria and contain nucleaus and other strucure , mire like an animal than a plant cell

Answer 19

protozoa

Question 20

protozoa loves moisuture T OR F

Answer 20

t

Question 21

characteristics of protozoa

Answer 21

1. all protozoa are heterotrophic
2. doesnt have rigid cell wall, but have elastic membrane that permits movement
3. produces asexually (binarymultiple fission)
   4.

Question 22

what is heterotrophic

Answer 22

they derived their nutrients from other organism by consuming their organic remains

Question 23

what are the 4 groups of protozoa

Answer 23

1. amoeboid protozoan/sarcodines
2. flagellated /zooflagellate
3. ciliated protozoan
   4, sporozoan

Question 24

what group of protozoan that have examples such like

• amoeba dysentery
• entamoeba hystolitica
• entamoeba gingivalis

Answer 24

amoeboid protozoan

Question 25

what group of protozoan that lives at the termite intestine

Answer 25

flagellated

Question 26

what group of protozoan that have examples such like - vorticella - balantidium coli

Answer 26

cilliated protozoan

Question 27

what group of protozoan that have examples such like | -plasmodium spp

Answer 27

sporozoan

Question 28

malaria is an insect bite from

Answer 28

anopheles mosquito that has plasmodium

Question 29

trypanosomiasis is a bite from:

Answer 29

tsestse fly

Question 30

leishmaniasis bite from

Answer 30

sand fly

Question 31

protozoal intestinal infection that causes severe diarrhea amd epigrastric distress leading to serious malnutrition

Answer 31

giardiasis

Question 32

protozoan causes vaginitis in women

Answer 32

trichomoniasis

Question 33

type of malaria: the most dangerous type of protozoan

Answer 33

plasmodium falciparum

Question 34

type of malaria: milder form of disease, seldom results in death

Answer 34

plasmodium vivax

Question 35

type of malaria: tropical countries, mild syntoms

Answer 35

plasmodium malariae

Question 36

type of malaria: rarely seen, process of being eradicated

Answer 36

plasmodium ovale

Question 37

antimalarial actions of various stages stages: acting againts the RBC phase of the life cycle

Answer 37

schizontocidal

Question 38

antimalarial actions of various stages stages: acting againsts the gametocyctes

Answer 38

gamitocidal

Question 39

antimalarial actions of various stages stages: acting againts the parasite that are developing in the mosquito or work againsts tissue shizonts as prophylactic

Answer 39

sporontocidal

Question 40

what are the different antimalarial actions of various stages stages:

Answer 40

schizontocidal gametocytocidal sporontocidal

Question 41

site of action: what does sporontocidal drugs do in the life cycle of mosquitos/ cycle of humans?

Answer 41

active againsts the parasite developing in the mosquito

Question 42

what are the sporontocidal drugs?

Answer 42

- pyrimethamine | - primaquine

Question 43

site of action: what does gametocytocidal drugs do in the life cycle of mosquitos/ cycle of humans?

Answer 43

active againsts the gametocytes of all malaria parasites

Question 44

what are the gametocytocidal drugs

Answer 44

primiquine

Question 45

what are the gametocyte-sterilizing drugs

Answer 45

pyrimethamine

Question 46

site of action: what does schizontocidal drugs do in the life cycle of mosquitos/ cycle of humans?

Answer 46

active againsts the erythrocytic phase

Question 47

what are the schizontocidal drugs

Answer 47

pyrimethamine | hydroxychloroquine

Question 48

site of action: what does antirelapse drugs do in the life cycle of mosquitos/ cycle of humans?

Answer 48

secondary tissue schizont in liver cell

Question 49

what are the antirelapse drugs drugs

Answer 49

primaquine

Question 50

site of action: what does causal prophylactic drugs drugs do in the life cycle of mosquitos/ cycle of humans?

Answer 50

primary tissue schizont in liver cell

Question 51

what are the causal prophylactic drugs

Answer 51

- pyrimethamine | - primaquine

Question 52

sign and syntoms of malaria

Answer 52

related to the destruction of RBC and toxicity of liver

Question 53

treatment of malaria

Answer 53

aims to attacking the parasite at the various stages of its development inside and outside of the human body

Question 54

types of antimalarial drugs in relation to the stages in the plasmodium life cycle

Answer 54

pic sa page 186

Question 55

use of antiprotozoal therapay across lifespan: | children

Answer 55

verysensitive and more severe reaction

Question 56

use of antiprotozoal therapay across lifespan: >adult > pregnant and nursing women > older adult

Answer 56

a: need of prophylaxis and immediate treatment p and n: benefits outweight its risk o: more suspectible to adverse effects

Question 57

what are the antimalarial drugs?

Answer 57

``` chloroquine mefloquine primaquine pyrimethamine quinine ```

Question 58

the mainstay of antimalarial therapy

Answer 58

chloroquine

Question 59

prevention and treatment of plasmodial malaria; treatment of extraintestinal amebiasis

Answer 59

chloroquine

Question 60

treatment of plasmodial malaria in combination with other drugs (particulary primaquin)

Answer 60

hydroxychloroquine

Question 61

what antimalarial drugs for prevention and treatment of plasmodium malaria; treatment for extraintestinal amebiasis

Answer 61

chloroquine

Question 62

what antimalarial drugs for prevention and treat,ent for plasmodium malaria in combination with other drugs

Answer 62

mefloquine

Question 63

what antimalarial drugs for prevention of relapses of plasmodium vivax and plasmodium malariea ; radical cure of P. vivax malaria

Answer 63

primaquine

Question 64

prevention of plasmodium malaria in combination with other agents to supress transmission; treatment of toxoplasmosis

Answer 64

pyrimethamine

Question 65

treatment of uncomplicated malaria caused by plasmodium falciparum

Answer 65

quinine

Question 66

treatment for chloroquine resistant plasmodial infection

Answer 66

quinine

Question 67

what is the antimalarial indication

Answer 67

to prevent acute malarial reaction in individuals who have been infected by the parasite

Question 68

what is the antimalarial action

Answer 68

ebter human red blood cells and change metabolic pathway necessary for reproduction

Question 69

intestinal infection caused by entamoeba histolytica known as amebic dysentery

Answer 69

amebiasis

Question 70

an infection where the sand fly inject an asexual form flagellated protozoan called promastigote but digested by macrophage, but inside the macrophage it develops into amastigote that will eventually kill macrohage and it will releseas and another macrophage will eat then then same cycle again

Answer 70

leishmaniasis

Question 71

amastigote causes lesions in skin, viscera, mucuous membrane of host

Answer 71

amastigote

Question 72

caused by trypanosoma

Answer 72

trypanosomiasis

Question 73

____-african sleeping , sickness caused by ____live in blood then attacks CNS , leads to acute inflammation leads to lethargy , prolomged sleep, death

Answer 73

trypanosomiasis; tseste fly

Question 74

when individuals have aids they are immunosupressed then parasite able to infect lungs leading to severe inflammation knowns as

Answer 74

pneumocystis jiroveci pneumonia

Question 75

preventon and treatment for pneumocystis jiroveci pneumonia and combination iwht chloriquine

Answer 75

atovaquone

Question 76

treatment for amebiasis, trichomonaiasis, giardiasis

Answer 76

metronidazole

Question 77

treatment of diarrhea asssoiated with guardia lamblia

Answer 77

nitrazoxanide

Question 78

an inhalation treatment for pneumocystis jiroveci | and systemic agent treatment of trypanosomiasis and leishmaniasis

Answer 78

pentamidine

Question 79

treatment for trichomoniasis, giardiasis, amebiasis

Answer 79

tinidazole

Question 80

what are the common antiprotozoal agents: | np mt a

Answer 80

-------

Question 81

what chloroquine do inside the parasite?

Answer 81

metabolic pathway

Question 82

what mefloroquine do inside the parasite?

Answer 82

acidic protzoal vacuole food

Question 83

what do inside the primaquinine parasite?

Answer 83

mitochondria, gametocyte, exocrythrocytic

Question 84

what do inside the pyramethamine parasite?

Answer 84

folic acid

Question 85

what do inside the quinine parasite?

Answer 85

glucolis, nucliec and protein synthesis