Antiprotozoals Flashcards
1
Q
Synthetic ani-pneumocystis Med
A
Pentamidine (Pentam 300)
MOA: inhibits protein and nucleic acid synthesis; also has a direct effect on pancreatic islet cells. Disrupts glucose and amino acid metabolism
Indications: Pneumocytsis Jirovecii, pneumonia treatment or prophylaxis (which is actually a fungal infection but this med works best)
Hypersensitivity more common in inhaled form
2
Q
Amebicide Med
A
Metronidazole (Flagyl)
MOA: directly kills protozoa by causing free radical reaction that damages DNA
Indications: amebiasis, trichomoniasis, giardiasis, acne, rosacea, c-diff
A/E: sz, dizzy, h/a, meningitis, encephalopathy, abd pain, anorexia, n/d
