Antiretroviral Agents

Question 0

Zerit XR

Answer 0

stavudine=d4T

-nucleoside RTI

Question 1

Retrovir

Answer 1

zidovudine=AZT

-nucleoside RTI

Question 2

Epivir

Answer 2

lamivudine=3TC

-nucleoside RTI

Question 3

Tyzeka

Answer 3

telbivudine

-nucleoside RTI

Question 4

Videx EC

Answer 4

didanosine=ddI

• nucleoside RTI
• take on an EMPTY stomach*

Question 5

Ziagen

Answer 5

abacavir

-nucleoside RTI

Question 6

Emtriva

Answer 6

emtricitabine

-nucleoside RTI

Question 7

Viramune

Answer 7

nevirapine

-non-nucleoside RTI

Question 8

Rescriptor

Answer 8

delavirdine

-non-nucleoside RTI

Question 9

Sustiva

Answer 9

efavirenz

• non-nucleoside RTI
• take on an EMPTY stomach

Question 10

Intelence

Answer 10

etravirine

-non-nucleoside RTI

Question 11

Edurant

Answer 11

rilpivirine

-non-nucleoside RTI

Question 12

Viread

Answer 12

tenofovir

-nucleotide RTI

Question 13

Truvada

Answer 13

emtricitabine, tenofovir

• combination RTI
• qdaily
• now approved for prophylaxis of HIV in high-risk adults

Question 14

Atripla

Answer 14

efavirenz, emtricitabine, tenofovir

• combination RTI
• take on an EMPTY stomach

Question 15

Combivir

Answer 15

zidovudine, lamivudine

-combination RTI

Question 16

Epzicom

Answer 16

abacavir, lamivudine

-combination RTI

Question 17

Trizivir

Answer 17

abacavir, lamivudine, zidovudine

-combination RTI

Question 18

Complera

Answer 18

emtricitabine, rilpivirine, tenofovir

-combination RTI

Question 19

Viracept

Answer 19

nelfinavir

• protease inhibitor
• take WITH food

Question 20

Lexiva

Answer 20

fosamprenavir

• protease inhibitor
• take WITH food

Question 21

Invirase

Answer 21

saquinavir

• protease inhibitor
• take WITH food

Question 22

Norvir

Answer 22

ritonavir

• protease inhibitor
• take WITH food

Question 23

Crixivan

Answer 23

indinavir

• protease inhibitor
• take on an EMPTY stomach

Question 24

Reyataz

Answer 24

atazanavir - protease inhibitor * take WITH food

Question 25

Aptivus

Answer 25

tipranavir - protease inhibitor * take WITH food and also with ritonavir for ritonavir boosting

Question 26

Prezista

Answer 26

darunavir - protease inhibitor * take WITH food and also with ritonavir for ritonavir boosting

Question 27

Kaletra

Answer 27

lopinavir, ritonavir - combination protease inhibitor * take WITH food

Question 28

Isentress

Answer 28

raltegravir | -integrase inhibitor- another enzyme HIV needs to replicate

Question 29

Selzentry

Answer 29

maraviroc | -CCR5 antagonist- prevents HIV from entering the T-cell by blocking CCR5 receptors so HIV can't get inside

Question 30

Fuzeon

Answer 30

enfuvirtide - fusion inhibitor- prevents HIV from entering the T-cell by altering the virus and preventing it from fusing to the two receptors - subQ injection

Question 31

classes of antiretroviral agents (5)

Answer 31

``` reverse transcriptase inhibitors protease inhibitors integrase inhibitors fusion inhibitors CCR5 antagonists ```

Question 32

3 types of RTIs

Answer 32

nucleoside RTIs non-nucleoside RTIs nucleotide RTIs

Question 33

nucleoside RTIs (7)

Answer 33

``` Retrovir Zerit XR Epivir Videx EC Ziagen Emtriva Tyzeka ```

Question 34

non-nucleoside RTIs - 5

Answer 34

``` Viramune Rescriptor Sustiva Intelence Edurant ```

Question 35

RTI action

Answer 35

inhibit reverse transcriptase which is an enzyme that HIV needs to replicate; disease progression is slowed if inhibited

Question 36

ind. of antiretroviral agents

Answer 36

treat infections caused by retroviruses

Question 37

antiretroviral agent pt. couseling

Answer 37

-DON'T SKIP DOSES

Question 38

what is the point of ritonavir boosting?

Answer 38

when taken with Aptivus, Prezista, and Kaletra; ritonavir inhibits the enzyme that metabolizes these drugs to increase the level of the drug

Question 39

combination RTIs (6)

Answer 39

``` Truvada Atripla Combivir Epzicom Trizivir Complera ```

Question 40

protease inhibitors (9)

Answer 40

``` Viracept Lexiva Invirase Norvir Crixivan Reyataz Aptivus Prezista Kaletra ```

Question 41

HAART

Answer 41

Highly Active AntiRetroviral Therapy - used for HIV - involves taking multiple antiretroviral agents from different classes at the same time