Antiulcer Flashcards Preview

NUR 409 Pharmacotherapeutics > Antiulcer > Flashcards

Flashcards in Antiulcer Deck (9)
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1
Q

peptic ulcer dz (PUD) increased risk

A
helicobacter pylori - main cause
meds (NSAIDS (ketorolac), corticoseroids, bisphosphates, chemo)
stress
smoking
tobacco
ETOH
acidic foods
2
Q

mechanism of proton pump inhibitors

A

inhibit function of proton pumps at gastric mucosal lining

3
Q

proton pump inhibitor meds

A
-prazoles
omeprazole
esomeprazole
pantoprazole
lansoprazole
4
Q

common uses of proton pump inhibitors

A

peptic ulcer dz
GERD
heartburn

5
Q

issues w/proton pump inhibitors

A

slow onset, short half-life
don’t crush/chew; take before breakfast
rebound sx: reflux, heartburn, gas
may cause: pneumonia, osteoporosis, hypomagnesemia

6
Q

H2 blocker meds

A

ranitidine
cimetidine
famotidine

7
Q

H2 blocker mechanism of action

A

block histamine in stomach to mildly aid problem (not as strong as proton pump inhibitors which block BOTH pumps)

8
Q

issues w/ H2 blockers

A

diminished effect over time
robound sx if abruptly stopped
confusion w/poor renal function

9
Q

sucralfate

A

coats stomach up to 6h

take before meals and 2h b/w other meds d/t absorption interference