Anxiety Flashcards
(28 cards)
SSRIs for MDD
Citalopram
Escitalopram
Fluoxetine
Paroxetine
Sertraline
SSRIs for GAD
Escitalopram
Paroxetine
SSRIs for OCD
Fluoxetine
Fluvoxamine
Paroxetine
Sertraline
SSRIs for Panic
Fluoxetine
Paroxetine
Sertraline
SSRIs for PTSD
Paroxetine
Sertraline
SSRIs for SAD
Paroxetine
Sertraline
SNRIs for MDD
Desvenlafaxine
Duloxetine
Venlafaxine
Levomilnacipram
SNRIs for GAD
Duloxetine
Venlafaxine
SNRIs for Panic
Venlafaxine
SNRIs for SAD
Venlafaxine
How long do Antidepressants take to have anti-anxiety effects fro GAD?
2 - 4 weeks
Antidepressant side effects
Sexual dysfunction
Weight gain
Drowsiness
Benzodiazepine receptors
A1 - Sedation
A2 - Anxiolysis
Contraindications of BZDs
Myasthenia gravis
Hepatic Dysfunction
Narrow angle glaucoma
Respiratory disorders
Pregnancy/Lactation
High potency BZDs
clonazepam
lorazepam
Anterograde Amnesia BZDs (high affinity to receptor)
Alprazolam
Triazolam
High lipophilic BZD
diazepam
clorazepate (needs acid)
Low lipophilic BZDs
Oxazepam
lorazepam
BZDs for Anxiety
Lorazepam
Alprazolam
Clorazepate
Diazepam
Chlorazepoxide
PKPD of high lipophlic BZDs
Faster rate of absorption (alprazolam)
Large Vd
Shorter Duration of Action
PKPD of low lipophilic BZDs
Slower rate of absorption
Smaller Vd
Larger Duration of Action (clonazepam)
Which BZDs bypass liver metabolism
Oxazepam
Temazepam
Lorazepam
Which BZD is a prodrug?
Clorazepate - needs acid
Which Anxiety med needs increased doses during pregnancy
Lithium
