Bipolar Disorder

Question 1

APSs used in Bipolar Disorder

Answer 1

Aripiprazole
Asenapine
Cariprazine
Lumateperone
Lurasidone
Olanzapine
Quietapine
Risperidone
Ziprasidone

Question 2

BPD Medications for Acute Mixed/Mania

Answer 2

Li,VPA
Carbamezapine
Aripiprazole
Asenapine
Cariprazine
Olanzapine
Quietapine
Risperidone
Ziprasidone

Question 3

BPD Medications for Maintenance

Answer 3

Lithium
Lamotrigine
Aripiprazole
Olanzapine
Quietapine
Risperidone
Quietapine

Question 4

BPD Medications for Acute Depression

Answer 4

Cariprazine
Lumateperone
Lurasidone
Olanzapine
Quietapine

Question 5

What are considered mood stabilizers

Answer 5

Any medications used to treat bipolar disorder

Question 6

Long-Acting Injectables used for BPD

Answer 6

Aripiprazole
- Maintena
Risperidone
- Consta

Question 7

True or False. First Gen Antipsychotics have antimanic properties

Answer 7

True

Question 8

True or False. BZDs have antimanic properties

Answer 8

True

Question 9

What is the long term adverse effect on Lithium

Answer 9

Kidneys (polydipsia and polyuria)
Thyroid (hypothyroidism)

Question 10

How is Lithium metabolized?

Answer 10

Not Hepatically

Question 11

What are the adverse effects of lithium?

Answer 11

Renal function (BUN &Scr)
GI
CNS
Muscle weakness Lethargy
Cardiac Effects
Blood dyscrasia (Clozapine)

Question 12

What medications must you avoid to avoid lithium toxicity

Answer 12

NSAIDS
ACEi
ARBs
Diuretics

***drugs that affect the renal function

Question 13

True or False. Lithium is safe to use in nursing mothers

Answer 13

False. It is contraindicated

Question 14

True or False. Lithium serum concentration levels are related to therapeutic response

Answer 14

False

Question 15

What enhances neurotoxicity with Lithium use

Answer 15

Calcium Channel Blockers
ECT

Question 16

What AEDs are approved in BPD?

Answer 16

Lamotrigine
Valproic Acid
Carbamazepine ER (Equetro not Tegretol)

Question 17

Valproic acid side effects

Answer 17

Weight gain
GI irritation
prolonged bleeding
Alopecia

Question 18

Valproic acid BBW

Answer 18

Pancreatitis
Hepatotoxicity
Urea disorder

Question 19

How should you initiate Lamotrigine

Answer 19

Slow Titration

Question 20

What should you do the dose of lamotrigine when used in combo with Valproic acid

Answer 20

Halve the dose of lamotrigine

Question 21

What is a serious side effect of Lamotrigine

Answer 21

SJS rash

Question 22

What are the side effects if Carbamazepine?

Answer 22

Neutropenia
Leukopenia
Hematologic Disease
Agranulocytosis
Asian: HLA-B*1502 (increased risk of SJS/TEN)

Question 23

True or False. You can use antidepressants exclusively to treat BPD depression

Answer 23

False

Question 24

What class of Antidepressants and result in switch to mania?

Answer 24

TCAs (&SNRIs)

Question 25

What is in Lybalvi

Answer 25

Olanzapine Samidorphan

Question 26

What is the purpose of samidorphan in olanzapine

Answer 26

Reduce metabolic symptoms of olanzapine

Question 27

What is Lybalvi indicated for?

Answer 27

Schizophrenia Bipolar Disorder

Question 28

What is the contraindication with Lybalvi

Answer 28

Use of opioids Acute Opioid Withdrawal