Schizophrenia

Question 1

1st gen Antipsychotics

Answer 1

Chlorpromazine
Fluphenazine
Haloperidol
Perphenazine
Thioridazine
Thiothixene

Question 2

What 1st gen Antipsychotics are available as Long Acting Injectables?

Answer 2

Fluphenazine
Haloperidol

Question 3

1st gen Antipsychotics ADEs

Answer 3

EPS
QTc Prolongation
Prolactin Elevation
Dermatologic
Photo-sensitivity
Blue-gray skin
Orhtostatic hypotension
Altered thermoregulation

Question 4

2nd gen Antipsychotics

Answer 4

Aripiprazole
Asenapine
Brexipiprazole
Cariprazine
Clozapine
Iloperidone
Lumateperone
Lurasidone
Olanzapine
Paliperidone
Quietapine
Risperidone
Ziprasidone

Question 5

What 2nd gen Antipsychotics are used to treat MDD?

Answer 5

Aripiprazole
Brexipiprazole
Olanzapine (w/ fluoxetine)
Risperidone

Question 6

Which 2nd gen Antipsychotics are available as long acting injectable?

Answer 6

Aripiprazole
Olanzapine
Paliperidone
Risperidone

Question 7

2nd gen Antipsychotics ADEs

Answer 7

Metabolic syndrome
Qtc Prolongation
Blood dyscrasias/neutropenias
Seizure thresholds
Anticholinergic effects
Sedation
Prolactin Elevation
Ophthalmic effects

Question 8

Which antipsychotics are FDA-approved for use in pediatrics

Answer 8

Aripiprazole
Lurasidone
Olanzapine
Paliperidone
Quietapine
Risperidone

Question 9

Which Antipsychotic comes with NIOSH guidelines?

Answer 9

Ziprasidone

Question 10

What is the BBW associated with antipsychotics?

Answer 10

Dementia - related psychosis

Question 11

Which 1st gen Antipsychotics require a PO overlap?

Answer 11

Fluphenazine
Haloperidol

Question 12

Which 2nd gen Antipsycotics require a PO overlap?

Answer 12

Aripiprazole
Risperidone

Question 13

Describe Acute Dystonia

Answer 13

Long painful contractions
Stiffnes

Question 14

Treatment for Acute Dystonia

Answer 14

Anticholinergics
IM BZDs

Question 15

Describe Pseudo-Parkinsonism

Answer 15

Bradykinesia

Question 16

Treatment for Pseudo-Parkinsonism

Answer 16

Anticholinergics

Question 17

Describe Akathasia

Answer 17

Restlessness
Pacing around

Question 18

Treatment for Akathasia

Answer 18

Beta blockers

Question 19

Describe Tardive Dyskinesia

Answer 19

Tongue thrusting
lip biting
Chewing

Question 20

Treatment for Tardive Dyskinesia

Answer 20

Prevention

Question 21

What medication should you not use in Tardive Dyskinesia

Answer 21

Anticholinergics as they mask the symptoms of tardive Dyskinesia

Question 22

Beta blockers used in Akathasia

Answer 22

Nadolol
Propranolol
Metoprolol

Question 23

Benzodiazepines used in EPS Treatment

Answer 23

Clonazepam
Diazepam
Lorazepam

Question 24

Medications for EPS Treatment

Answer 24

Diphenhydramine
Benztropine
Trihexyphenidyl
Amantadine
BZDs

Question 25

What drugs are used fro VMAT2 inhibition?

Answer 25

Valbenazine Deutetrabenazine

Question 26

What is the caution with the benazines?

Answer 26

Hepatic impairment ContraI with Deutetra

Question 27

What 2nd Gen Antipsychotics can cause EPS?

Answer 27

Risperidone Paliperidone

Question 28

What 2nd Gen Antipsychotics cause the most weight gain?

Answer 28

Clozapine Olanzapine Quetiapine

Question 29

What 2nd gen Antipsychotics cause the least weight gain?

Answer 29

Aripiprazole Lurasidone Ziprasidone

Question 30

What 2nd gen Antipsychotics are most sedating?

Answer 30

Quetiapine Clozapine

Question 31

What APS are high potency

Answer 31

Fluphenazine Haloperidol

Question 32

Which APS are low potency

Answer 32

Chlorpromazine Thioridazine

Question 33

What 1st gen APS are the most sedating?

Answer 33

Chlopromazine Thioridazine

Question 33

Which 1st gen APS cause the most EPS?

Answer 33

Fluphenazine Haloperidol