App 10 - Pharmacokinetics Flashcards
(48 cards)
1
Q
do you know?
A
review
2
Q
How does ionization od drugs by the body affect their transport?
A
3
Q
How are pH, pKa, and drugs related?
A
4
Q
What are pH partitions in drug distribution?
A
5
Q
How do we conceptualize drug ionization and pH and pKa?
A
6
Q
A
7
Q
A
8
Q
What are some common log values?
A
9
Q
A
10
Q
A
11
Q
A
12
Q
A
13
Q
A
14
Q
A
15
Q
A
16
Q
A
17
Q
What is ion trapping? What is its role in aspirin overdose? What about methamphetamines?
A
18
Q
A
19
Q
A
20
Q
A
21
Q
A
22
Q
What are therapeutic dosing regimens and what parameters need to be considered in them?
A
23
Q
What is volume of distribution (Vd)?
A
24
Q
how do you calculate Volume of distribution (Vd)?
A
25
26
27
What is drug clearance (CL)? How do you calculate it?
28
What is Bioavailability (F)? How do you calculate it?
29
30
What s drug half life and how do you calculate it?
31
32
33
What is a rational dosing regimen?
34
What is a maintenance does and how do you calculate it?
35
What is a loading dose and how do you calculate it?
36
37
What are some limiations of pharmacokinetics?
38
What is therapeutic drug monitoring?
39
40
41
42
43
44
45
46
47
48
