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Ph Ch 128 2nd Exam > Aromatic Polyketides > Flashcards

Aromatic Polyketides Flashcards

(58 cards)

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0
Q

Source of 6-methylsalicylic acid

A

Penicillium patulum

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1
Q

5 examples of simple phenols

A

Orsellinic acid, phloroacetophenone, 6-methylsalicylic acid, alternariol, lecanoric acid

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2
Q

Source of alternariol

A

Alternaria tenuis

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3
Q

Oxygenation on alternate carbon atoms

A

Meta oxygenation pattern

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4
Q

Ester from 2 phenolic acids

A

Depside

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5
Q

Examle of depside

A

Alternariol

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6
Q

Consists of 3 rings and a quinone

A

Anthraquinones

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7
Q

Sugars of anthraquinones

A

Glucose and rhamnose (sometimes apiose)

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8
Q

Classification of anthraquinones

A

Oxanthrone, anthrone, dianthrone, anthranol

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9
Q

Relieve constipation

A

Danthron

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10
Q

Treat psoriasis

A

Dithranol

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11
Q

Treat osteoarthritis

A

Diacetylrhein

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12
Q

Relieve depression and photosensitation

A

Hypericin

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13
Q

Source of mycophenolic acid

A

Penicillium brevicompactum

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14
Q

Other name for mycophenolate mofetil

A

N-morpholinoethyl ester

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15
Q

Precursor of mycophenolic acid

A

5-methylorsellinic acid

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16
Q

Inhibitor of mammalian inosine monophosphate dehydrogenase

A

Mycophenolic acid

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17
Q

Source of furochromones (khellin and visnagin)

A

Ammi visnaga

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18
Q

Treat angina pectoris and bronchial asthma

A

Khellin

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19
Q

Synthetic analogue of khellin; for treat,ent and prophylaxis of asthma, hay fever, and allergic rhinitis

A

Cromoglicate

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20
Q

Source of hyperforin and adhyperforin

A

Hypericum perforatum (Fam. Hypericaceae)

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21
Q

Source of humulone

A

Humulus lululus (Fam. Cannabaceae)

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22
Q

Source of usnic acid

A

Usnea and Cladonia sp.

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23
Q

Source of griseofulvin

Study These Flashcards
A

Penicillium griseofulvum

24
Responsible for bitter taste of beer
Humulone
25
Antidepressive agent
Hyperforin and Adhyperforin
26
Use of usnic acid
Antibacterial
27
Use of griseofulvin
Antifungal
28
From type III chalcone synthase
Chalcones
29
Precursor of chalcones
Cinnamoyl Coa
30
From type III stilbene synthase
Stilbenes
31
Starter group of stilbenes and chalcones
Cinnamoyl CoA
32
Source of resveratrol
Vitis vinifera L. (Fam. Vitaceae)
33
Source of lunularic acid
Lunularia cruciata (Fam. Lunulariaceae)
34
Precursors of quinoline alkaloids
L-tryptophan and secologanin
35
Starter group of quinoline alkaloids
Anthraniloyl CoA
36
Use of quinidine
For cardiac arrhythmia
37
Use of quinine
Antimalarial
38
Starter group of acridine alkaloids
Anthraniloyl CoA
39
Source of anacardic acid
Anacardium occidentalis L. (Fam. Anacardiaceae)
40
Starter group of anacardic acid
Palmitoleoyl CoA
41
Contact allergens
Urushiols
42
Sources of urushiols
Toxicodendrom radicans and T. toxicaria
43
Source of cannabinoids
Cannabis sativa (Fam. Cannabaceae)
44
Starter group of aflatoxin
Hexanoate
45
Starter group of tetracyclins
Malonamyl CoA
46
Extender of tetracyclins
Malonyl CoA
47
Sources of aflatoxin
Aspergillus flavus and A. parasiticus
48
Starter group of anthracyclines
Propionate
49
Exterder group of anthracyclines
Malonyl CoA
50
Source of doxorubicin
Streptomyces peuceticus var. caesius
51
Other name for doxorubicin
Adriamycin
52
Source of daunorubicin
Streptomyces coeruleorubicus
53
Other name for daunorubicin
Daunomycin
54
Semi synthetic anthracycline used for treatment of breast cancer
Epirubicin
55
Semi synthetic anthracycline that is anti-leukemic
Aclarubicin
56
Semi synthetic anthracycline with high activity and low cardiotoxicity
Idarubicin
57
Other name for mitozantrone
Mitoxantrone

Ph Ch 128 2nd Exam (7 decks)

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