Arterial Diseases of the Limb Flashcards

(89 cards)

1
Q

What causes upper limb vascular disease

A
Stenosis - atherosclerosis 
Thrombosis
Inflammation
Emboli
Venous disease
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2
Q

What is collateral circulation

A

If main vessel occluded collateral takes over

May not be sufficient if high metabolic demand

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3
Q

What does axillary / brachial emboli cause

A

6P’s

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4
Q

What causes axillary emboli

A

AF so may have features e.g. syncope

Mural thrombus from LA

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5
Q

What causes arterial occlusion

A

Atherosclerosis

Trauma is rare

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6
Q

What are the symptoms of arterial occlusion

A

Claudication
Ulceration
Gangrene
Subclavian steal if proximal

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7
Q

What causes venous thrombosis in upper limb

A

Pre-exisitng malignancy

Repetitive use

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8
Q

How do you treat

A

Same as DVT
Gradual onset swelling and discomfort
Sensation and motor = normal

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9
Q

What is cervical rib

A

Fibrous band arising from 7th cervical vertebrae
Congenital or traumatic
Presents 3rd decade

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10
Q

What are the symptoms

A

Thoracic outlet syndrome

Absent radial and +Ve Adson if compress subclavian

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11
Q

What is Adson

A

Flexion away from symptomatic side + traction of symptomatic obliterates radial

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12
Q

How do you treat

A

Surgery

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13
Q

What causes subclavian steal

A

Proximal stenosis of subclavian artery
Causes retrograde flow through vertebral or internal thoracic
Decrease through carotid = syncope, dizzy, vertigo
Brain stem ischaemia like Sx
Typically when using arm
>20mmHg pressure difference in arms

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14
Q

How do you Dx and Rx

A

Duplex and angio

ANgiplasty and stent

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15
Q

What causes peripheral arterial disease / RF

A
Atherosclerosis = main cause 
HTN 
Smoking = strong link 
Cholesterol 
DM = atheroma / calcification 
CKD 
Stroke / TIA / MI / angina - other arterial disease
Previous PCI / CABG 

Non modifiable
Male
Age
FH

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16
Q

What is PAD classified into

A

Intermittent
Acute limb ischaemia
Chronic limb ischaemia - symptomatic
Critical

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17
Q

What are less common causes of peripheral arterial disease

A

Vasculitis

Buerger’s in young smoker

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18
Q

What is Buerger’s / Thromboanngiits obliterates

A

Young male smoker
Ischaemia - claudication / ulcers- UL and LL
Superficial thrombilitis
Raynaud’s

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19
Q

What is stage 1 chronic limb ischaemia

A

Asymptomatic as incomplete obstruction

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20
Q

What is stage 2

A

Mild intermittent claudication = BMT
- Cramping pain after walking and improved rest
A >200m
B <200m

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21
Q

What is stage 3

A
Rest pain 
Particularly at night 
Patients often hang legs of bed to ease pain
If buttock = iliac pain
If calf = superficial femoral
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22
Q

What is stage 4

A

Necrosis
Ulceration
Gangrene
Toes and heels common

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23
Q

What is critical limb ishcaemia

A
1+ of
Rest pain >2 weeks
Ulceration
Gangrene
Requires urgent investigation and investigation
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24
Q

What do you look for in the examination

A
Ulcers
Hair loss 
Pain
Pallor
Parathesia
Perishingly cold
Pulses - popliteal and feet just say present or absent 
CRT - prolonged 
Paralysis 
Aneurysm - aorta
Carotid bruit 
BP both arms 
Quality - thumbing, normal, weak, absent
Size - small, normal, ecstatic, aneurysmal 
Soft, hard, calcified
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25
How do you investigate PAD What is 1st line imaging Other imaging options
``` H+E Bloods - FBC, U+E, lipid, blood glucose for DM, Thrombophilia screen if <50 ECG for cardiac ischaemia Assess pulses Bueger's ABPI Doppler USS ``` If stage 3 Arterial Duplex (USS + doppler) = 1st line MR angiogram if considering intervention CT angiogram if CI i.e. due to pacemaker (radiation / contrast nephropathy) / or to plan Rx - looks like normal CT CT / MRI Digital subtraction angiography (invasive as puncture artery) - X-Ray
26
What is the ABPI
Ratio of BP in legs (posterior tibial or dorsals pedis) to arms (brachial artery) Use hand held doppler + BP cuff to get Should be >8 If <1 = PAD Won't work if calcified will be inappropriately high - DM / low sun / 2 PTH / CKD / via D deficiency
27
What are the stages of PAD related to ABPI
``` >1 = asymptomatic (0.9-1.2) or calcification - DM / CKD 0.5-0.95 = intermittent claudication / absent distal 0.3-0.5 = severe refer as critical limb ischaemia / Bueger +ve / absent distal / ulceration / rest pain <0.2 = gangrene ```
28
What is Buerger's test
Elevate legs and look at pallor Go pale at lower degrees <20 = indicate severe ischaemia >90 = normal Hang over bed and skin goes bright red due to loss of auto regulation / slow to return = +ve sign
29
How do you treat PAD
``` Modify CVS RF If >200 = BMT If <200m = stent / angioplasty If rest pain = urgent referral for stent or surgical bypass Amputation if not possible / gangrene ```
30
What does bypass require
Good influx of blood Conduit vein Aorta - femoral Femoral femoral bypass if don't want to use aorta due to chest
31
What does BMT involve
``` Anti-platelet - single clopidogrel > aspirin Statin BP control Stop smoking Exercise - supervised Weight loss Diabetic control Vascular clinic follow up ```
32
What is important in the history
Vascular RF Exercise tolerance Claduciation pain - effect of incline/. changes SOCRATES Any rest pain Tissue loss - duration / trauma / sensation
33
What causes acute limb ischamia
Emboli - Post MI - Atrial fibrillation Arterial thrombus from stenosed artery Rare cause Trauma Dissection
34
What are the symptoms
``` 6P's - Pale - Pulseless - Pain - Paraesthesia - Paralysis - Perishingly cold Always compare to contralateral Irreversible after 6 hours ```
35
How do you Dx
``` Dx = clinical as Ix delays RX History - critical ischaemia / cardiac / onset and duration Bloods ECG Doppler USS - absent CT angio to image ```
36
How do you Rx
Discuss with senior NBM Analgesia Anti-coagulate - IV heparin infusion to prevent extension URGENT surgery - bypass or stent / embolectomy Can do on table angio +- tPA thrombosis if fails Amutation if not salvageable Life-long anti-coagulation required after
37
What are complications of acute limb ischaemia
Compartment syndrome
38
What are types of amputation
``` Hind quarter Hip disarticulation - more trauma / malignancy Transfemoral (above knee) Through knee Transtibial (below knee) - less energy Symes Transmetatarsal Digit ```
39
What are reasons for amputation
Bypass / angioplasty not an option Peripheral vascular disease Trauma Malignancy
40
Who are at risk of needing
DM Atherosclerosis Adrenaline large dose = vasoconstriction -> gangrene
41
Who is at risk of high mortality from amputation
``` Age Co-morbid CVS disease DM Blood loss / GA Coronary and cerebral artery disease ```
42
What are complications of amputation
``` Stump breakdown Wound infection DVT /PE HAP Phantom limb MI / stroke - optimise CVS / BMT Falls Mortality ```
43
What causes stump breakdown
Ischaemia / poor blood - higher amputation may be needed Infection Trauma - control falls Control BG
44
How do you prevent DVT
LMWH admission to discharge
45
What do you do if DM of digit
Transmetatarsal as risk other toes will become affected
46
How do you minimise pain
Neuropathic pain relief | Wound catheter giving LA
47
Anatomy of LL
Aorta Common iliac Internal iliac External iliac -> superficial femoral at inguinal ligament Posterior tibial -> dorsalis pedis -> pedal arch Collateral - profunda femoris, anterior tibial, peroneal
48
How does DM worsen ulceration
Neuropathy | Microvascular complications
49
What is claudication
Cramp like pain in back of calfs when blood supply to muscle is reduced Worse up hills Relieved by rest Progressive but reduced by formation of collateral
50
What do you do before bypass surgery
``` H+E ECG FBC, U+E, LFT, coag, glucose, G+S CXR PFT / ECHO / myocardial perfusion scan ```
51
What are the complications of bypass surgery
``` MI Infection Pneumonia Stroke Limb loss PE / DVT Graft failure ```
52
What arteries affected by PAD
Coronary Carotid Peripheral
53
USS
Dynamic images and flow 1st line if not severe / IC Non-invasive, no radiation, done at bedside User dependent
54
MR angiogram
Contrast safer than CT Better soft tissue contrast Not if pacemaker Less available
55
CT angiogram
``` Inject contrast IV Take photos in arterial phas Good resolution Less invasive Radiation, nephrotoxic Can't visualise if calcified Useful if deciding anatomy ```
56
Angiogrpahy
``` X-Ray used Have to puncture artery to inject Can do angioplasty / stent after if vessel found to be stenosed High radiation Nephrotoxic contrast ```
57
Angioplasty
Catheter and balloon to open up artery | Only 15% suitable
58
When is stent used
If multiple Long stenosis Failed angio
59
Embolisation
``` Fibroid AV Tumour GI bleed Endoleak post EVAR Trauma Varciocele ```
60
What can DM cause
``` Peripheral neuropathy Peripheral vascular disease OM Neuropathic pain Charcot Ulceration ```
61
What causes foot ulcers
Ischaemia Neuropathy Mixed
62
What causes neuropathy
Microvascular complication = nerve hypoxia | Hyperglycaemia = affects metabolism
63
Symptoms of neuropathy
Asymptomatic Burning pain Altered temp sensation Altered touch - allydonia where touch perceived as pain Autonomic = reduced sweat / loss of auto regulation Motor = muscle wasting and deformity Charcot
64
How do you Dx neuropathy
Regular foot exam
65
How do you Rx
Footwear
66
How do you treat diabetic foot
Surgical debridement | Amputation may be needed
67
What are types of pain people with PVD / DM can present with
Neuropathic Ischaemic Intermittent claudication
68
Neuropathic pain
``` Foot / shin Tingling / burning Night time worse Exercise better Warm foot Bounding pulse ```
69
Ischaemic pain
``` Foot / calf Aching pain Elevation worsen Hanging foot = better Feet cold Pulsless ```
70
Intermittent claudication
``` Calf / thigh Cramping Exercise worse Rest better Weak or absent pulse ```
71
What causes Charcot
DM neuropathy
72
What is stage 1
``` Fragmentation Swelling Red Warmth X-Ray shows soft tissue swelling / bony fragmentation / dislocation ```
73
What is stage 2
Coalescenece X-Ray shows healing Reduced swelling
74
What is stage 3
Reconstruction | X-Ray shows residual deformity
75
What is anterior triangle of neck bordered by
SCM Mandible Midline Clavicle
76
What is posterior triangle of the neck bordered by
SCM | Trapezius
77
What is the contents of the anterior triangle
``` Common carotid Internal carotid External carotid Vagus nerve (runs beside CCA) Hypoglossal and accessory nerve ```
78
What is the contents of the posterior triangle
Subclavian artery and vein Brachial plexus Occipital artery Nerves
79
What are the branches of the external carotid
``` Superior thyroid Acending pharyngeal Lingual Occpital Facial Posterior auricular Maxillary Superficial temporal ```
80
What makes up popliteal fossa
Biceps femoral (lateral) Semimembranous Plantaris Gastrocnemius
81
Contents of popliteal fossa
Sciatic branches into tibial and common fibular Popliteal vein and artery Sural nerve
82
When do you do carotid endarectomy
>70% stensosis | Symptomatic - Arthrus fujax / TIA / stroke
83
Why don't you do angioplasty in carotid
High risk of stroke / emboli
84
What if you don't do endarectomy
1 in 5 will have another event | 1 in 100 will have stroke due to op
85
If someone presents with pain down their leg what do you ask
Ask red flag - caudal equina Weight loss / B symptoms Surgical Hx
86
If man has pain in buttocks when walks but no calf what vessel
Iliac
87
What vessel if calf pain
Femoral
88
What causes Leriche
Occlusion in distal aorta / iliac
89
What is the triad
Thigh / buttock claudication Absent femoral pulses Male impotence