Aspergillus fumigatus Flashcards

(11 cards)

1
Q

soort

A

fungus => schimmel

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2
Q

epidemiologie

A
  • Bodem, rottend plantenmateriaal, water, lucht, voedsel
  • Besmetting via inhalatie van sporen
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3
Q

Pathogenese

A
  • Normaal = weinig pathogeen
  • allergische reacties
  • groei in vooraf bestaande holte (aspergilloom)
  • verminderde weerstand: sporen ontkiemen en de hyfen dringen in weefsel en BV
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4
Q

ziektebeelden

A
  • allergische reactie
  • kolonisatie
  • chronische pulmonaire aspergillose bij ernstige immuun-suppresie en na ernstige covid- of influenza-infectie
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5
Q

vb. allergische reactie

A

astma bij atopie

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6
Q

vb kolonisatie

A

aspergilloom in vooraf bestaande holtes zoals sinus

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7
Q

diagnose

A

combinatie van voorbeschikking, klinisch + radiologisch beeld en microbiologie

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8
Q

behandeling normaal

A

voriconazol

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9
Q

behandeling bij resistentie

A

lipid-Amphotericine B

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10
Q

bij hoog risico, preventie

A

opvolging galactomannan in bloed

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11
Q

preventie

A

profylaxe met azole

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