Assessment Of Bioavailability Flashcards by Лили Ауси

Q

What is the most commonly used method of assessing the bioavailability of a drug

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Q

Explain the plasma concentration time curve until it reaches Cmax

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Q

Explain the ascending part of the graph

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Q

Explain the descending portion of the graph

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Q

Explain the elimination phase of the graph

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Q

Define onset

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Q

Define duration

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Q

Define peak concentration

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Q

Define time to peak concentration

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Q

Define the Area under the plasma concentration time curve

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Q

What are the factors that can complicate the interpretation of bioavailability studies

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Q

Explain the cumulative urinary drug excretion curves

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Q

What are the limitations of cumulative urinary drug excretion curves

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Q

Define the absolute bioavailability

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Q

How can absolute bioavailability be calculated

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Q

Define relative bioavailability

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Q

What is bioequivalance

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Q

How is bioequivalence assessed

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Q

Why is bioequivalence important

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Q

What are the types of equivalency

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Pharmaceutical equivalence
Pharmaceutical alternatives
Bioequivalent drug products
Therapeutic equivalence

Q

Define pharmaceutical equivalence

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Q

Explain the key conditions of pharmaceutical equivalence

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Q

Give an example of pharmaceutical equivalence

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Q

Define pharmaceutical alternatives

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What are the key differences of pharmaceutical alternatives

Give example of pharmaceutical alternatives

Define bioequivalent drug products

Explain the key criteria for bioequivalent drug products

Give example of bioequivalent drug products

Define therapeutic equivalence

Explain the key criteria of therapeutic equivalence

Give example of therapeutic equivalence

What is the BCS