Autoimmunity Flashcards

Dr. Denzin

1
Q

Loss of AIRE function leads to compromised _____ Selection in the Thymus

A

Negative

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2
Q

Immune Dysregulation Polyendocrinopathy Eteropathy X-linked (IPEX) happens with a mutation in _____ gene, where children die within the first 2 years of life.

A

FOXP3

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3
Q

_____ Proteins can explain why environmental factors such as smoking can modify “Self” and cause autoimmunity

A

Citrullinated

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