autoimmunity

Question 1

Genetic factors

Answer 1

B27- ankylosing spondylitis
DR2- Good pasture syndrome
DR3- Sicca syndrome

Question 2

autoimmunity

Answer 2

ankylosing spondylitis

affects more males

Question 3

organ specific A.I

Answer 3

Endocrine glands

Question 4

pemphigus and pemphigoid

Answer 4

Pemphigus affects the outer of the skin (epidermis) and causes lesions and blisters that are easily ruptured. Pemphigoid affects a lower layer of the skin, between the epidermis and the dermis, creating tense blisters that do not break easily. Sometimes pemphigoid may look like hives or eczema without blisters.

Question 5

SLE

Answer 5

DNA specific T cells escape the thymus
T cell help and low level antibodies against DNA
-infection leading to apoptosis and interferon secretion
DNA/antibody complexes

Question 6

problem

Answer 6

non specific

suppress immune system