immunity Flashcards

1
Q

passive immunity

A

Snake or spider bites, scorpion or fish stings

intravenous immunoglobulin

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2
Q

direct

A

bi specific antibodies
monoclonal antibodies
Chimeric antigen

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3
Q

indirect

A

tumour vccines
dendrtic cell
adoptive cell transfer

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4
Q

cytokine therapies

A

pegylated interferon alpha, IL-2, GM -CSF

immunomodulatory cytokines

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5
Q

monoclonal antibodies

A

immunisation
fusion& immortalisation of B cells
isolation and screening
expansion of desired hybridoma

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6
Q

rituximab

A

first line treatment for non hodgkin
specific for CD20 molecule on the cell surface of subpopulation of B cells
effective on rheumatic arthritis

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7
Q

new anti-HER2 antibodies

A

pertuzumab differs from trastuzumab (herceptin) because it is directed at the dimerisation of HER2 - disruption of dimer formation

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8
Q

risankizumab

A

psoriatic arthritis

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9
Q

check point inhibitors

A

antibodies unlock the gateway to the adaptive immune system

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