Autonomic Nervous System Flashcards Preview

Pharmacology > Autonomic Nervous System > Flashcards

Flashcards in Autonomic Nervous System Deck (21):
1

Alpha 1 receptor agonists and usage (2)

Phenyphidrine
Oxymetazoline (ophthalmology)

Nasal decongestants

2

Alpha 1 receptor antagonists and usage (5)

Prazosin - HT
Doxazosin
Terazosin
Tamulosin - prostatic hypertrophy
Resperine

3

Alpha 2 receptor

Auto-inhibition

4

Meaning of auto-inhibition

When the substance binds to the receptor it is taken up, thus the effect will decrease.

5

Alpha 2 receptor agonists and usage

Clonidine - reduce BP
Methyldopa - BP in pregnancy

6

Alpha 2 receptor antagonists (3)

Mianserin
Phentolamine
Phenoxybenzamine

7

Beta 1 receptor agonists and usage

Dobutamine - cardiogenic shock

8

Beta 1 receptor antagonists

Atenolol
Propanolol - acute sinus bradycardia

9

Beta 2 receptor agonists and usage

Salbutamol
Terbutaline
Salmeterol

Bronchodilators
Stop labour

10

Beta 2 receptor antagonists

Propanolol

11

Reuptake inhibitors

Cocaine
TCA

12

Reuptake inhibitors side effects

CNS - euphoria, excitement
Tachycardia
Cardiac arrhythmias

13

Drugs interfering with catecholamine synthesis

Methyldopa
Alpha-methyltyrosine - phaeochromocytoma
Carbidopa
6-hydroxydopamine and MPTP - neurotoxins: destroy nerves after its taken up

14

Reserpine

Block NA take up into vesicles
Used as anti-hypertensive

15

Nicotinic receptor agonists

Nicotine
Lobeline

16

Nicotinic receptor antagonist

Hexamethonium
Trimetaphan

17

M2 - receptor agonists

Pilocarpine - glaucoma

18

M2 - receptor antagonists

Atropine

19

M3 receptor agonists

Pilocarpine
Bethanechol - bladder emptying and GIT motility increase

20

Enzyme inactivators

Donepezil
Physostigmine
Neostigmine
Pyridostigmine

21

Parasympatholytics

Atropine - antispasmodic, organophosphate poisoning
Scopolamine - motion sickness
Ipratopium - bronchodilator
Cyclopentolate - myadrisis
Tropicandine - eye drops
Pirenzipine - PUD
Oxybutinin - urinary incontinence