Autonomic Nervous System Agonists and Antagonists Flashcards
(36 cards)
What is phenylephrine?
Alpha 1 Agonist
Therapeutic effect of phenylephrine?
Decrease in nasal congestion
Maintain BP
Max number of days to use phenylephrine?
3 days
Where are Beta 2 receptors located?
Lungs
Arterioles
Uterus
Liver
GI Tract
Where are Beta 1 receptors located?
Heart
Coronary Vessels
Kidneys
What are the Adrenergic Receptors?
Alpha 1
Alpha 2
Beta 1
Beta 2
3 Ways to inactive neurotransmitter?
Diffusion
Re-uptake
Enzyme degradation or transformation
What is the parasympathetic system neurotransmitter?
acetylcholine
Where are muscarinic receptors located?
Internal organs
Where are nicotinic receptors located?
Skeletal Muscles
Motor Nerves
What are the cholinergic receptors?
Muscarinic
Nicotinic
What is a cholinergic crisis?
Excessive parasympathetic stimulation
-miosis
-N/V
-urinary incontinence
-increase in secretions
-tachycardia then bradycardia
-hyperglycemia
What medication do you give in cholinergic crisis?
Atropine
What to adrenergic antagonists do?
Block SNS
Decrease Heart Rate, BP and Anxiety
What is a cholinergic agonist medication?
bethanechol
What are the therapeutic effects of epinephrine?
Decrease allergic reactions
Treat anaphylaxis
Is epinephrine selective or nonselective?
nonselective
What are the therapeutic effects of propranolol?
Decrease hypertension, angina, and anxiety
Side effects of propranolol?
IMPOTENCE
hypoglycemia in diabetics
What is propranolol?
beta adrenergic antagonist
(nonselective for beta 1 or beta 2)
What is prazosin?
Alpha 1 antagonist
What are the therapeutic effects of prazosin?
Lower HTN, treat BPH, and PTSD
What are the therapeutic effects of bethanecol?
decrease urine retention
increase peristalsis and GI secretions
What is albuterol?
Beta 2 agonist