Autonomic Nervous System Agonists and Antagonists Flashcards

(36 cards)

1
Q

What is phenylephrine?

A

Alpha 1 Agonist

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2
Q

Therapeutic effect of phenylephrine?

A

Decrease in nasal congestion
Maintain BP

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3
Q

Max number of days to use phenylephrine?

A

3 days

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4
Q

Where are Beta 2 receptors located?

A

Lungs
Arterioles
Uterus
Liver
GI Tract

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5
Q

Where are Beta 1 receptors located?

A

Heart
Coronary Vessels
Kidneys

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6
Q

What are the Adrenergic Receptors?

A

Alpha 1
Alpha 2
Beta 1
Beta 2

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7
Q

3 Ways to inactive neurotransmitter?

A

Diffusion
Re-uptake
Enzyme degradation or transformation

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8
Q

What is the parasympathetic system neurotransmitter?

A

acetylcholine

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9
Q

Where are muscarinic receptors located?

A

Internal organs

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10
Q

Where are nicotinic receptors located?

A

Skeletal Muscles
Motor Nerves

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11
Q

What are the cholinergic receptors?

A

Muscarinic
Nicotinic

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12
Q

What is a cholinergic crisis?

A

Excessive parasympathetic stimulation
-miosis
-N/V
-urinary incontinence
-increase in secretions
-tachycardia then bradycardia
-hyperglycemia

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13
Q

What medication do you give in cholinergic crisis?

A

Atropine

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14
Q

What to adrenergic antagonists do?

A

Block SNS
Decrease Heart Rate, BP and Anxiety

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15
Q

What is a cholinergic agonist medication?

A

bethanechol

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16
Q

What are the therapeutic effects of epinephrine?

A

Decrease allergic reactions
Treat anaphylaxis

17
Q

Is epinephrine selective or nonselective?

18
Q

What are the therapeutic effects of propranolol?

A

Decrease hypertension, angina, and anxiety

19
Q

Side effects of propranolol?

A

IMPOTENCE
hypoglycemia in diabetics

20
Q

What is propranolol?

A

beta adrenergic antagonist
(nonselective for beta 1 or beta 2)

21
Q

What is prazosin?

A

Alpha 1 antagonist

22
Q

What are the therapeutic effects of prazosin?

A

Lower HTN, treat BPH, and PTSD

23
Q

What are the therapeutic effects of bethanecol?

A

decrease urine retention
increase peristalsis and GI secretions

24
Q

What is albuterol?

A

Beta 2 agonist

25
Therapeutic effects of albuterol?
improve asthma, COPD
26
What are 3 Adrenergic Agonists?
Albuterol Epinephrine Phenylephrine
27
Where are Alpha 1 Receptors located?
Blood vessels Eyes Bladder Prostate
28
Where are Alpha 2 Receptors located?
Blood Vessels Smooth Muscle (GI)
29
What is the neurotransmitter for the sympathetic nervous system?
Norepinephrine
30
What medication is a muscarinic antagonist?
atropine sulfate
31
What are the therapeutic effects of atropine sulfate?
Increase HR Dilate pupils Dry secretions Slow GI tract Treat cholinergic crisis
32
Sxs of anticholinergic?
Can't Pee Can't See Can't Spit Can't Shit
33
Beta 1 Agonist sxs?
Increased Heart Rate Increased BP Increased Renin secretion
34
Beta 2 Agonists sxs?
Bronchiole dilation Decreased GI motility Increased blood flow to skeletal muscles Increase blood glucose
35
Alpha 2 Agonists sxs?
Decrease in vasoconstriction Decrease in BP Decrease in GI motility
36
Alpha 1 Agonists sxs?
Increase force of heart contraction vasoconstriction Increase BP Pupil Dilation Prostate contraction and ejaculation