B2.077 Cell Biology Collagen Flashcards Preview

MCM Test 1 > B2.077 Cell Biology Collagen > Flashcards

Flashcards in B2.077 Cell Biology Collagen Deck (17)
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1
Q

what are 3 functions of the basal lamina?

A

structure: anchors epithelium to basement membrane
sifting: barrier between blood and urine in glomerulus
signaling: present signaling molecules to the epithelium

2
Q

what are the 6 primary components of connective tissue?

A

cells, extracellular matrix, supporting tissues, basement membranes, cartilage, bone

3
Q

what makes up the extracellular matrix

A

fibers: collagen and elastin

ground substance: GAGs, protein core

4
Q

what are the two subtypes of connective tissue?

A

proper: well organized

specialized

5
Q

what are the 2 subtypes of proper connective tissue and their subsequent subtypes?

A

loose> areolar, adipose, or reticular

dense> regular, irregular, or elastic

6
Q

what are the 3 subtypes of specialized connective tissue and their subtypes?

A

bone> spongy and compact
blood
cartilage>elastic, hyaline, fibrocartilage

7
Q

which type of collagen is found in reticular tissue and is found in wound healing?

A

type 3

8
Q

what collagen types primarily make up proper dense tissues?

A

1 & 2

9
Q

what are the resident connective tissue cells?

A

fibroblasts (chondroblasts, osteoblasts, odontoblasts)

adipocytes

10
Q

what are the transient connective tissue cells?

A

macrophages, plasma cells, mast cells, lymphocytes, eosinophils

11
Q

what is the most abundant protein in the body?

A

collagen 1

12
Q

what enzyme catalyzes the covalent linkage of collagen fibers?

A

lysyl oxidase

13
Q

what cells secrete collagen?

A

fibroblasts

14
Q

what type of collagen is found alongside type 1 but in smaller amounts?

A

type 5

15
Q

what helps link collagen fibrils together in the fiber?

A

type 5 collagen

16
Q

what makes a syndrome autosomal dominant?

A

you see the phenotype expressed

17
Q

whats more common, deficiencies in actin or collagen?

A

collagen

actin are fatal