B2.077 Cell Biology Collagen Flashcards Preview

MCM Test 1 > B2.077 Cell Biology Collagen > Flashcards

Flashcards in B2.077 Cell Biology Collagen Deck (17):
1

what are 3 functions of the basal lamina?

structure: anchors epithelium to basement membrane
sifting: barrier between blood and urine in glomerulus
signaling: present signaling molecules to the epithelium

2

what are the 6 primary components of connective tissue?

cells, extracellular matrix, supporting tissues, basement membranes, cartilage, bone

3

what makes up the extracellular matrix

fibers: collagen and elastin
ground substance: GAGs, protein core

4

what are the two subtypes of connective tissue?

proper: well organized
specialized

5

what are the 2 subtypes of proper connective tissue and their subsequent subtypes?

loose> areolar, adipose, or reticular
dense> regular, irregular, or elastic

6

what are the 3 subtypes of specialized connective tissue and their subtypes?

bone> spongy and compact
blood
cartilage>elastic, hyaline, fibrocartilage

7

which type of collagen is found in reticular tissue and is found in wound healing?

type 3

8

what collagen types primarily make up proper dense tissues?

1 & 2

9

what are the resident connective tissue cells?

fibroblasts (chondroblasts, osteoblasts, odontoblasts)
adipocytes

10

what are the transient connective tissue cells?

macrophages, plasma cells, mast cells, lymphocytes, eosinophils

11

what is the most abundant protein in the body?

collagen 1

12

what enzyme catalyzes the covalent linkage of collagen fibers?

lysyl oxidase

13

what cells secrete collagen?

fibroblasts

14

what type of collagen is found alongside type 1 but in smaller amounts?

type 5

15

what helps link collagen fibrils together in the fiber?

type 5 collagen

16

what makes a syndrome autosomal dominant?

you see the phenotype expressed

17

whats more common, deficiencies in actin or collagen?

collagen
actin are fatal