B6.052 Large Group Osteoporosis

Question 1

why do men have lower rate of osteoporotic fracture

Answer 1

greater periosteal bone formation

Question 2

clinical risk factors for BMD testing in adults aged 50-64

Answer 2

fragility fracture after 40
prolonged steroids
other high risk meds
parental fracture of hip
vertebral fracture or osteopenia on xray
current smoking
high alcohol intake
low body weight or major weight loss
RA

Question 3

what is a DEXA scan

Answer 3

most accurate way to measure BMD
quick, easy, painless
low dose x-ray (10% of CXR)

Question 4

errors that occur with bone density

Answer 4

osteophytes and vascular calcifications are common in aging men
vertebral fracture artificially increased bone density
hip is most reliable spot for diagnosis and response to therapy

Question 5

BMD independent risk factors for fracture in men

Answer 5

quadriceps strength
body sway
prevalent vertebral fracture

Question 6

reversible causes of osteoporosis

Answer 6

HPTH
celiac
hypogonadism

Question 7

hypogonadism and osteoporosis

Answer 7

decrease in testosterone with aging

individuals with multiple comorbidities have lower testosterone

Question 8

multiple myeloma and osteoporosis

Answer 8

can present with fracture

screen w serum and urine electrophoresis

Question 9

daily elemental calcium recommendation

Answer 9

1200-1500 mg

Question 10

what % of pts on steroid get fractures

Answer 10

30-50%

fracture risk up to 15% in first year of treatment

Question 11

factors that contribute to glucocorticoid induced osteoporosis

Answer 11

highest rate of bone loss occurs in first 3-6 months

both high daily doses and cumulative dose