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MCD - Microbiology- Laz > Bacterial Disease > Flashcards

Flashcards in Bacterial Disease Deck (16):
1

What type of bacteria do you find in the small intestine?

Gram-negative

2

Give some examples of bacteria and viruses that use the upper respiratory tract as a portal of entry.

Neisseria meningitidis
Influenza
Parainfluenza
Streptococcus pneumoniae
Streptococcus pyogenes
Staphylococcus aureus

3

Give some examples of intrinsic bacteria that can infect via the urogenital tract.

E. coli
Klebsiella
Candida

4

Give some examples of extrinsic bacteria that can infect via the urogenital tract.

Chlamydia
Syphillis
Neisseria gonorrheae

5

Give examples of bacteria that can infect via broken skin.

Staphylococcus aureus
Streptococcus pyogenes

6

State some consequences of infection via broken skin.

Abscess formation
Bacteraemia
Necrotic infection

7

Give some examples of bacteria and viruses that infect via the gastrointestinal tract.

Vibrio cholera
Salmonella
Listeria
Shigella
E. coli
Campylobacter jejuni

8

What are some consequences of infection via the gastro-intestinal tract?

Diarrhoea
Bacteraemia/systemic infections

9

What two main factors affect pathogenecity?

Infectivity and Virulence

10

Define infectivity.

The ability of a pathogen to establish infection

11

Define virulence.

The ability of a pathogen to cause disease

12

Define infectious dose.

Number of bacteria needed to cause infection

13

Describe how vibrio cholerae causes disease.

It uses its flagella to propel itself into the mucosal membrane of the intestines.
It then begins producing toxins A and B, which bind to GM gangliosides and triggers production of cAMP
This leads to chloride efflux and hence movement of water into the lumen from the cells

14

State whether each of the following are Gram-positive or Gram-negative:

Shigella - negative
Streptococcus - positive
Listeria - positive
Clostridium - positive
Vibrio cholerae - negative
E. coli - negative
Salmonella - negative
Staphylococcus - positive
Neisseria - negative
Haemophilus influenzae - negative

15

Give two examples of Gram-negative opportunistic bacteria.

Pseudomonas aeruginosa
Acinetobacter baumanii

16

Give two examples of Gram-positive opportunistic bacteria.

E. faecalis
Staphylococcus epidermidis