Bacterial Infections Flashcards Preview

Question 1

1

Tx for neonatal profylaxis of gonorrhea and chlamydia

Answer

Erythromycin ointment

Question 2

2

Tx for bacterial conjunctivitis

Answer

Gentamycin, Tobramycin (Aminoglycosides)

or

Azithromycin (Macrolide)

or

Bactrim (sulfa)
**ADR, corneal ulcer** Interacts w SILVER

or

Ofloxacin, Ciprofloxacin, etc (Fluoro)
**ADR, photophobia**

Question 3

3

Tx for acute otitis externa

Answer

1. Acetic Acid (mild)

2. Polymyxin B / Neomycin Drops

Question 4

4

Tx chronic otitis externa

Answer

Polymyxin B / Neomycin drops

Question 5

5

Tx for "malignant " otitis externa - usually caused by pseudomonas, DM patients more prone - infection has spread to surrounding tissue / bone

Answer

Medical emergency, IV antibiotics and debridement

Question 6

6

1st line Tx for Acute Otitis Media

Answer

Amoxacillin

Augmentin with resistance

Question 7

7

PCN allergic Tx for acute otitis media

Answer

Cefdinir or Ceftriaxone

If anaphylaxis Rx >> Macrolide (Clarithro, Azithro)

Question 8

8

Gonorrhea and Chlamydia, treating togehter

Answer

Ceftriaxone IM + Azithromycin

Question 9

9

Nasal decolonization of MRSA

Mupirocin

Answer

1. Augmentin (after 2 weeks of sinusitis)

PCN allergic: Cephalsporin (Cefdinir, Ceftriaxone)
if Analphylactic allergic: Macrolide (Clarithro, Azithro)

Answer

Augmentin
or
Amoxiicllin / Ampicillin
or
Pen VK **black hairy tongue**

Answer

Cephalosporins

1st gen: Ceph-alexin, Ceph-adroxil, Cef-azolin

2nd gen: Cef-prozil, Cef-otetan, Cef-uroxime

3rd gen: Ceftriaxone?

4th gen: Cefepime

5th gen: Ceftaroline (MRSA)

Answer

(Most like S. pneumonia)

1. Azithromycin, Clarithromycin, Erythromycin (Macrolides)

Answer

1. Respiratory Fluoroquinolone
Moxifloxacin, Gemifloxacin, Levofloxacin

Answer

Amoxicillin / Augmentin + Azithro or Clarithro

PCN allergic:

Ceftriaxone + Azithro or Clarithro

Answer

Moxi, Levo, Gemi (resp fluoroquinolone)

**also good for PCN allergic**

Answer

(same as 2nd line CAP outpatient w chronic dz)

Amoxicillin / Augmentin + Azithro or Clarithro

PCN allergic:

Cetriaxone + Azithro or Clarithro

Answer

Cefotaxime, Ceftriaxone, Ampicillin + Levo, Moxi, Gemi

PCN allergic: AZTREONAM + Levo, Moxi, gemi

Answer

Joint cartilage injury in kids <16 yrs

Answer

Levofloxacin + B Lactam + Gentamycin (Aminoglycoside)

Answer

Antacids! (Mg, Ca)

Separate dose by 2 hours

Answer

Inhibit DNA gyrase and Topoisomerase IV (X DNA)

Answer

Levofloxacin

Answer

Levofloxacin + LINEZOLID or VANCOMYCIN

Answer

Clarithromycin

Answer

Sulfa Trimethoprime

Answer

Inhibits biosynthesis of bacterial nucleic acids and proteins (X DNA)

Bacteriocidal

Answer

Inhibit protein synthesis by binding 50 S ribosome (X DNA)

Bacteriostatic

Answer

Azithromycin is NOT a P450

Erithro and Clarithro P450!! -
show up in Breast Milk and Cross Placenta

Answer

Vancomycin

1. with Levo for CAP

2. with Ceftriaxone, Ampicillin, and Dexamethasone for Meningitis

3. Piperacillin or tazobactam for STD

Answer

Piperacillin or Tazobactam

with Gentamycin

Answer

1st line: Ceftriaxone with Azithromycin (presumptive tx of chlamydia too)

Answer

LIDOCAINE - very painful IM shot

Answer

Doxycycline

or Amoxicillin / Ampicillin

Answer

Teeth discoloration
Black tongue

Preg D

DON'T TAKE W DAIRY

Answer

CEFAZOLIN (1st gen cef)

Answer

Sulfa Trimethoprime
(avoid if used recently for UTI or if known resistance)

or

Nitrofurantoin

or

Fosfomycin

Answer

Ciprofloxacin

Levofloxacin
(unless there is known community resistance)

Answer

Tendon issues, esp in adolescents

Answer

Metronidazole

Answer

Metallic taste

Alcohol toxicity, into with Disulfiram

NO USE IN 1ST TRIMESTER PREGNANCY

Answer

Clindamycin

Answer

Efinaconazole

Answer

Metronidazole

Vancomycin PO

Fidaxomycin

Question 10

10

Tx for bacterial sinusitis, 1st line and PCN allergic

Question 11

11

1st line Tx Strep Pharyngitis

Question 12

12

Tx for PCN allergic, Strep Pharyngitis

Question 13

13

1st line Tx for CAP, outpatient, no use of abx in the past 3 months

Question 14

14

1st line Tx for CAP, outpatient, WITH CHRONIC DZ or use of and in past 3 months

Question 15

15

2nd line Tx for CAP, outpatient, WITH CHRONIC DZ or use of abx in past 3 months

Question 16

16

1st line Tx for CAP INPATIENT, non-ICU

also good for PCN allergic

Question 17

17

2nd Line Tx for CAP INPATIENT, non-ICU

Question 18

18

1st line Tx for CAP, INPATIENT ICU

Question 19

19

Notable ADR of Fluoroquinolones

Question 20

20

Tx for known pseudomonas infection

Question 21

21

Fluoroquinalones interact with what common OTC medication

Question 22

22

Fluoroquinolone MOA

Question 23

23

1st line HAP Tx, no MDR risks, not recent abc use

Question 24

24

1st line HAP Tx, MRSA or mortality risks

Question 25

25

Pertussis Tx, 1st line

Question 26

26

Pertussis Tx, 2nd line

Question 27

27

Sulfonamide MOAs

Question 28

28

Macrolide MOAs

Question 29

29

Macrolides and P450

Question 30

30

1st line for sepsis caused by Community Acquired Pneumonia, Skin and Soft Tissue Disease and Meningitis

Question 31

31

1st line for sepsis caused by Intra-abdominal infections, Pelvic or UTI

Question 32

32

Gonorrhea Tx

Question 33

33

Ceftriaxone IM - the shot MUST be given with what??

Question 34

34

1st line Lyme Disease Tx

Question 35

35

Notable Doxycycline ADRs and warnings

Question 36

36

Perioperative Prophylaxis

Question 37

37

1st line Tx Uncomplicated UTI

(Absence of fever, flank pain, or other
suspicion for pyelonephritis
Able to take oral medication)

Question 38

38

Pyelonephritis or Complicated UTI

Question 39

39

Black Box warning for Fluoroquinalones

Question 40

40

1st line Tx ,Bacterial Vaginitis

Question 41

41

Metronidazole ADRs and warnings

Question 42

42

2nd line Tx, Bacterial vaginitis (if early preg or alcoholic)

Question 43

43

1st line Tx Oncomycosis

Question 44

44

Brainscape's Knowledge GenomeTM