basal ganglia part 1 Flashcards

(45 cards)

1
Q
A
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2
Q

The basal ganglia (basal nuclei) are a group of —– ——nuclei.

A

The basal ganglia (basal nuclei) are a group of functionally related nuclei.

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3
Q

Subthalamic Nucleus (STN)

A

located in diencephalon

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5
Q

Dopaminergic neurons

A

are located in dorsal part of the substantia nigra

(cmpact part

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6
Q

also located medially in ventral tegmental area.

A

Dopaminergic neurons

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7
Q

Substantia Nigra (SN)

Compact Part (SNc) and Reticular Part (SNr)

A

in midbrain

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8
Q
A
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10
Q
A
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12
Q
A
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13
Q

dopamine

A

“reward system

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14
Q

The substantia nigra (reticular part) functions with the

—–as the output from the —-.

A

The substantia nigra (reticular part) functions with the GPi as the output from the BG.

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16
Q

ventral region of continuity btwn caudate and putamen

A

striatum

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18
Q

lenticular nucleus

A

putamen

gpe

gpi

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21
Q

cognition processes and control of movements.

A

dopamine

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22
Q

dopamine

A

enjoyment and pleasure, which reinforces and motivates

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23
Q

extrapyramidal system”

A

describes the nuclei and pathways of the BG

termed in 1900 by early 1900s Kinnier Wilson

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24
Q

influences motor and non motor sysem

A

basal ganglia

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25
Q

A lesion to —- —— of the BG will disrupt movement

A

A lesion to one or more of the BG will disrupt movement

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26
Q

Absence of spontaneous movement/ slowness of movement

Inability to inhibit unwanted movements

A

A lesion to one or more of the BG

27
Q

TF BG directly innervate LMNs in the spinal cord or cranial nerve nuclei;

A

F BG do NOT directly innervate LMNs in the spinal cord or cranial nerve nuclei;

28
Q

TF lesion to one or more of the BG produce paralysis

A

lesion to one or more of the BG does not produce paralysis

29
Q

tf BG only influence motor actions

A

t BG only influence motor actions

30
Q

Hypokinetic Disorder

A

Parkinson’s Disease

31
Q

loss of dopaminergic neurons in the SNc

A

Parkinson’s Disease a hypokinetic disease

32
Akinesia/Bradykinesia: without (difficulty initiating) movement/ slowness of movement
Hypokinetic Disorder
33
Parkinson’s Disease
Rigidity: increase in muscle tone
34
Resting tremor:
rhythmic involuntary movement at rest in Parkinson’s Disease
35
Hypokinetic Disorder like parkinsons dispkay
Postural instability
36
Chorea:
rapid, abrupt and random movements (limbs, face) Hyperkinetic Disorders
37
Putamen
input from motor and somatosensory cortices influences motor output.
38
info from limbic cortex, hippocampus and amygdala
N. Accumben
39
emotional and behavioral functions.
N. Accumbens
40
Athetosis:
slow, writhing movements Hyperkinetic Disorders
41
Hyperkinetic Disorders
Types of abnormal involuntary movements
42
Ballism(“ballistic movement ”)
:violent, large-amplitude mvmts hyperkinetic disease
43
Huntington’s Disease (HD
progressive degeneration of projection neurons and local circuit neurons in the caudate and putamen.
44
TF in huntington;s disease a Hyperkinetic Disorders; Neurons that give rise to the indirect pathway are preferentially lost.
F Neurons that give rise to the indirect pathway are preferentially lost.
45
extensive ----- projections to the striatum;
extensive cortical projections to the striatum;
46
recivees info from cortical association areas and has a role in cognitive functions
Caudate
50
51
cognitive functions
Dorsolateral prefrontal Loop:
52
motor output.
motor loop
53
Orbitofrontal loop:
planning and initiating socially appropriate actions
54
Limbic loop
emotional and behavioral functions.
55
Oculomotor loop:
control of orientation and gaze.