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Flashcards in basal gg Deck (29)
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1
Q

Basal gg (made up of) = ____ + ______

A

striatum + globus pallidus

Striatum contains:
o Caudate -< nucleus accumbens>- putamen
o Nucleus accumbens is where the caudate and putamen meet

Globus pallidus :
o Globus pallidus external (aka lateral)
o Globus pallidus internal (aka medial)

2
Q

lentiform nucleus (made up of) = ______+_______

A

putamen + globus pallidus

3
Q

Substantia nigra (made up of) = ______+ _____

A

pars compacta + pars reticulate

4
Q

cc: ________: where dopamine neurons are located

A

pars compacta

cc: the part that dies in parkinson’s

5
Q

_______: help to move the eyes back and forth

A

pars reticulata

6
Q

name the (3) portions of the basal gg

A

archaestriatrum
paleostriatum
neostriatum

7
Q

Within the archaestriatum the _____ is located. This structure holds emotions like fear/aggression/ rage . located in the temporal lobe

A

amygdala

8
Q

_____& _____ are held in the paleostriatum.

What separates these 2 structures

A

caudate and putamen

internal capsule separates them
nucleus accumbens

9
Q

basal gg is at the center of the ______

A

telencephalon

10
Q

** Cortex and basal gg communicate with ea. other ____

A

ipsi

Cortex and basal gg communicate with the M contralateral

11
Q

**Cortex and basal gg communicate with the M _________

A

contralateral

** Cortex and basal gg communicate with ea. other ipsi

12
Q

** berebellum communicates with the M ____

A

ipsi

13
Q

Cortical input gives off _____

A

glutamate

Basal gg input gives off GABA-ergic
Midbrain nuclei input gives off Dopaminergic

14
Q

Basal gg input gives off____

A

GABA

Cortical input gives off glutamate
Midbrain nuclei input gives off Dopaminergic

15
Q

Midbrain nuclei input gives off____

A

dopaminergic

Cortical input gives off glutamate
Basal gg input gives off GABA-ergic

16
Q

List the Basal gg structure pathway

A

striatum –> globus pallidus –> VA/VL complex of Thalamus –> UMN in cortex

17
Q

_____ neurons are inhiboitory cells located in the striatum

A

Medium spiny neurons

18
Q

Medium spiny neurons receive axons from____

project to___

A

receive: Cortex & substantia nigra pars compacta
project: GPi & SNpr

19
Q

______: controls eyes through inhibition of the superior colliculus

A

SNpr

20
Q

SNpr controls eyes through the inhibition of the ____

A

superior colliculus

21
Q

GPi projects to the _________ of the thalamus

A

ventral anterior/ventral lateral complex (VA/VL)

22
Q

____ structure works with the motor cortex to kick starts the striatum in the direct basal gg pathway

A

sunstantia nigra pars compacta

23
Q

substantia nigra pars compacta acts on the ___ receptor to effect the striatum

A

D1

w/ dopamine

24
Q

striatum acts on the ___ receptor to stim the GPi

A

D2

releases GABA

25
Q

cc: W/o the _________ Parkinson pt’s only use the motor cortex to make movements

A

substantia nigra pars compacta

26
Q

the ______ stops the direct pathway circuit

A

cerebellum

27
Q

cc : lesion in the striato-thalamo-cortical pathway causes____
what pathway is this ?

A

direct pathway

causes bradykinesis

Parkinsons: there is a lesion so that substantia nigra pars compacta can not assist the motor cortex to start the striatum

28
Q

Dopamine from the SNpc is _____ in the direct pathway

A

excitatory

-D1 receptors

29
Q

Dopaminefrom the SNpc is _____ in the indirect pathway

A

inhibitory

-D2 receptors