Basiswetenschappen

Question 1

A pit formed by osteoclast

Answer 1

Howship’s lacunae => worden cutting cones

Question 2

Bias

Answer 2

Allocation bias
Selection bias
Recall bias
Ascertainment bias
Publication bias

Question 3

Types of study

Answer 3

Expert opinion
Case report/series
Case control study
Cohort study
Randomized clinical trial

Question 4

Necrotizing fasciitis

Answer 4

LRINEC score
CRP
wBC
Hb
Na
Glucose
Creatinine

Diagnose emergent frozen section

Question 5

Difficult to treat organisms (PJI)

Answer 5

Rifampicine resistant Staphylokokken
Ciprofloxacine resistant gram negatieven
Fungi

Question 6

Septisch artritis kinderen: pathogene

Answer 6

<3M:
- staph aureus
- groep B strep
- N gonnoree
- Candida

3M-5J
S aureus
Kingella klingae
Haemophillus influenzae
Groep A streptokokkekn

> 5j
S aureus
Groep A streptokokken
Gonnoree (adolescenten)

Question 7

R Satph aureus

Answer 7

Flucloxacillin

Question 8

R Coagulase Neg Staph

Answer 8

Staph epidermidis Vancomycine

Question 9

Streptokokken

Answer 9

Penicillin

Question 10

Enterokokken

Answer 10

Amixicilline

Question 11

Gram neg infecties

Answer 11

Ceftriaxone-Cedtazidim

Question 12

C Acnes

Answer 12

Penicillin

Question 13

Types wear

Answer 13

Verlies van volume van weight bearing surface
Abbrasive wear
- two body
- third body
Adhasive wear
Fatigue wear

Question 14

Corrosion

Answer 14

Unwanted dissolution of a metal in a solution.

Oxidation and reduction reaction.

Galvanic corrosion
Pitting corrosion
Crevice corrosion
Fretting corossion = crevice corossion + wear

Question 15

Viscositeit

Answer 15

Stroperigheid

Question 16

Polyethyleen

Answer 16

(C2H4)n

Question 17

Keramiek

Answer 17

Verbinding tussen metaal en niet-metaal element

Covalente binding: delen van elektron
Ionische binding: transfer van elektron

Question 18

Wettability

Answer 18

Lower friction

High wettability => low contact angle

Question 19

ALVAL

Answer 19

Aseptic Lumphocyte-dominant Vasculitis Associated Lesion

Question 20

Types polyethyleen

Answer 20

Virgin PE: before irradiation - no X-linking
Conventional PE: after irradiation - X-linked and free radicals
X-linked PE:
- Highly crosslinked and heat stabilised PE (melting or annealing)
- Vit E doped PE
- Vit E blended PE

Question 21

Lyophilization

Answer 21

Verhoogde druk + temperatuur + solvent + bestraling => verwijderen niet minerale fracties

Question 22

Supercritt procedure

Answer 22

CO2 in superkritische fase => teinigen van botenten

Question 23

Traagheidsmoment

Answer 23

Moments of inertia

Weerstand tegen buigen, verdraaien, samendrukken of rekken hangt af van de vorm van een voorwerp.

R^4

Question 24

Bot is piëzoelektrisch

Answer 24

Door mechanische krachten ontstaan potentiaalverschillen

Question 25

Therapie osteoporose

Answer 25

Calcium 1g Vit D 800IU Bisfosfonaten PO of IV 1xjaar. Inactiveert osteoclasten. Denosumab sc 1x6maand rankl inhibitor => remt vorming osteoclasten Teriparatide: PTH analoog

Question 26

Parathormoon functie

Answer 26

Nier: stimuleert reabsorptie Ca en excretie F Bot: stimuleert osteoclasten

Question 27

Vit D werking

Answer 27

Stimuleert Ca absorptie darmen Stimuleert osteoclast resorptie

Question 28

Microfracture plus

Answer 28

AMIC Maioregen BSTACarCel (chitosbased scaffold) Hyalifast

Question 29

Hysteresis

Answer 29

Stress-strain curve differing during loading and unloading. Strain energy is lost during loading and unloading.

Question 30

Shear stresses

Answer 30

When two forces are direct parallel to each other but not along the same line. => shearing force

Question 31

Viscoelastic biomaterials loading

Answer 31

More rigid when they are rapidly loaded

Question 32

Gustillo antibiotica therapie

Answer 32

I: Ceftriaxone II, III: + aminoglycoside (gentamycine Soil contaminant: + penicilline